Svetlana Kholodar
Affiliations: | Postdoc |
Area:
Biochemistry, enzymology, physical organic chemistry, organic chemistryGoogle:
"Svetlana Kholodar"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Andrew S. Murkin | grad student | SUNY Buffalo | |
| Amnon Kohen | post-doc | University of Iowa |
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Publications
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| Kholodar SA, Finer-Moore JS, Świderek K, et al. (2021) Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog. Biochemistry |
| Kholodar SA, Ghosh AK, Świderek K, et al. (2018) Parallel reaction pathways and noncovalent intermediates in thymidylate synthase revealed by experimental and computational tools. Proceedings of the National Academy of Sciences of the United States of America |
| Kholodar SA, Ghosh AK, Kohen A. (2017) Measurement of Enzyme Isotope Effects. Methods in Enzymology. 596: 43-83 |
| Kholodar SA, Kohen A. (2016) Noncovalent Intermediate of Thymidylate Synthase: Fact or Fiction? Journal of the American Chemical Society |
| Kholodar SA, Allen CL, Gulick AM, et al. (2015) The role of phosphate in a multistep enzymatic reaction: reactions of the substrate and intermediate in pieces. Journal of the American Chemical Society. 137: 2748-56 |
| Murkin AS, Manning KA, Kholodar SA. (2014) Mechanism and inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase. Bioorganic Chemistry. 57: 171-85 |
| Kholodar SA, Tombline G, Liu J, et al. (2014) Alteration of the flexible loop in 1-deoxy-D-xylulose-5-phosphate reductoisomerase boosts enthalpy-driven inhibition by fosmidomycin. Biochemistry. 53: 3423-31 |
| Kholodar SA, Murkin AS. (2013) DXP reductoisomerase: reaction of the substrate in pieces reveals a catalytic role for the nonreacting phosphodianion group. Biochemistry. 52: 2302-8 |