Andrew McIver

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2007-2012 North Carolina State University, Raleigh, NC 
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"Andrew McIver"
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Rohde JM, Karavadhi S, Pragani R, et al. (2021) Discovery and Optimization of 2-1λ-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer. Journal of Medicinal Chemistry
Urban DJ, Martinez NJ, Davis MI, et al. (2017) Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays. Scientific Reports. 7: 12758
McIver A, Zhang W, Liu Q, et al. (2016) Discovery of Macrocyclic Pyrimidines as MerTK-specific Inhibitors. Chemmedchem
Buchanan MK, Needham CN, Neill NE, et al. (2016) Glycoconjugated Site-selective DNA-Methylating Agent Targeting Glucose Transporters on Glioma Cells. Biochemistry
Zhang W, McIver AL, Stashko MA, et al. (2013) Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis. Journal of Medicinal Chemistry. 56: 9693-700
Govan JM, McIver AL, Riggsbee C, et al. (2012) Hydrogen peroxide induced activation of gene expression in mammalian cells using boronate estrone derivatives. Angewandte Chemie (International Ed. in English). 51: 9066-70
Govan JM, McIver AL, Deiters A. (2011) Stabilization and photochemical regulation of antisense agents through PEGylation. Bioconjugate Chemistry. 22: 2136-42
Dush MK, McIver AL, Parr MA, et al. (2011) Heterotaxin: a TGF-β signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos. Chemistry & Biology. 18: 252-63
Georgianna WE, Lusic H, McIver AL, et al. (2010) Photocleavable polyethylene glycol for the light-regulation of protein function. Bioconjugate Chemistry. 21: 1404-7
McIver AL, Deiters A. (2010) Tricyclic alkaloid core structures assembled by a cyclotrimerization-coupled intramolecular nucleophilic substitution reaction. Organic Letters. 12: 1288-91
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