Jakob Fuhrmann
Affiliations: | 2016 | Chemistry | The Scripps Research Institute, Scripps Florida |
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Parents
Sign in to add mentor| Tim Clausen | grad student | 2006-2010 | IMP Vienna |
| Paul R. Thompson | grad student | 2016 | The Scripps Research Institute, Scripps Florida |
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Publications
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| Bashore C, Jaishankar P, Skelton NJ, et al. (2020) Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine. Acs Chemical Biology |
| Brust R, Lin H, Fuhrmann J, et al. (2017) Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor. Acs Chemical Biology |
| Hughes TS, Shang J, Brust R, et al. (2016) Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy. Journal of Medicinal Chemistry |
| Fuhrmann J, Subramanian V, Kojetin DJ, et al. (2016) Activity-Based Profiling Reveals a Regulatory Link between Oxidative Stress and Protein Arginine Phosphorylation. Cell Chemical Biology |
| Fuhrmann J, Thompson PR. (2015) Protein Arginine Methylation and Citrullination in Epigenetic Regulation. Acs Chemical Biology |
| Fuhrmann J, Subramanian V, Thompson PR. (2015) Synthesis and Use of a Phosphonate Amidine to Generate an Anti-Phosphoarginine-Specific Antibody. Angewandte Chemie (International Ed. in English) |
| Fuhrmann J, Clancy KW, Thompson PR. (2015) Chemical Biology of Protein Arginine Modifications in Epigenetic Regulation. Chemical Reviews. 115: 5413-61 |
| Slade DJ, Fang P, Dreyton CJ, et al. (2015) Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design. Acs Chemical Biology. 10: 1043-53 |
| Schmidt A, Trentini DB, Spiess S, et al. (2014) Quantitative Phosphoproteomics Reveals the Role of Protein Arginine Phosphorylation in the Bacterial Stress Response. Molecular & Cellular Proteomics : McP. 13: 537-550 |
| Wang M, Fuhrmann J, Thompson PR. (2014) Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion. Biochemistry. 53: 7884-92 |