Marcus Fischer

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
Structural biology
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"Marcus Fischer"
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Stachowski TR, Nithianantham S, Vanarotti M, et al. (2023) Pan-Hsp90 ligand binding reveals isoform-specific differences in plasticity and water networks. Protein Science : a Publication of the Protein Society. e4629
Stachowski TR, Fischer M. (2022) Large-Scale Ligand Perturbations of the Protein Conformational Landscape Reveal State-Specific Interaction Hotspots. Journal of Medicinal Chemistry
Stachowski TR, Vanarotti M, Seetharaman J, et al. (2022) Water Networks Repopulate Protein-Ligand Interfaces With Temperature. Angewandte Chemie (International Ed. in English)
Bradford SYC, El Khoury L, Ge Y, et al. (2021) Temperature artifacts in protein structures bias ligand-binding predictions. Chemical Science. 12: 11275-11293
Darby JF, Hopkins AP, Shimizu S, et al. (2019) Water networks can determine the affinity of ligand binding to proteins. Journal of the American Chemical Society
Pottel J, Levit A, Korczynska M, et al. (2018) The Recognition of Unrelated Ligands by Individual Proteins. Acs Chemical Biology
Balius TE, Fischer M, Stein RM, et al. (2017) Testing inhomogeneous solvation theory in structure-based ligand discovery. Proceedings of the National Academy of Sciences of the United States of America
Lee H, Fischer M, Shoichet BK, et al. (2016) Hydrogen Bonding of 1,2-Azaborines in the Binding Cavity of T4 Lysozyme Mutants: Structures and Thermodynamics. Journal of the American Chemical Society
Fischer M, Hopkins AP, Severi E, et al. (2015) Tripartite ATP-independent periplasmic (TRAP) transporters use an arginine-mediated selectivity filter for high affinity substrate binding. The Journal of Biological Chemistry
Fischer M, Shoichet BK, Fraser JS. (2015) One Crystal, Two Temperatures: Cryocooling Penalties Alter Ligand Binding to Transient Protein Sites. Chembiochem : a European Journal of Chemical Biology
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