William F. DeGrado, Ph.D.
Affiliations: | 1996-2011 | University of Pennsylvania, Philadelphia, PA, United States | |
2011- | Pharmaceutical Chemistry | University of California, San Francisco, San Francisco, CA |
Area:
Organic Chemistry, Chemical Biology, De Novo Protein DesignWebsite:
http://www.degradolab.org/index.phpGoogle:
"William DeGrado"Bio:
http://www.nasonline.org/member-directory/members/3008580.html
http://pharmchem.ucsf.edu/faculty/bios/william.degrado.html
https://pharm.ucsf.edu/degrado/people/alumni
Mean distance: 7.3 | S | N | B | C | P |
Parents
Sign in to add mentorEmil Thomas Kaiser | grad student | 1981 | Chicago | |
(Design, synthesis, and mechanism of action of a model cytotoxic peptide) |
Children
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Publications
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Lu L, Gou X, Tan SK, et al. (2023) design of drug-binding proteins with predictable binding energy and specificity. Biorxiv : the Preprint Server For Biology |
Wallace HM, Yang H, Tan S, et al. (2023) Design of Peptides that Bind Specific Conformers of α-Synuclein. Biorxiv : the Preprint Server For Biology |
Somberg NH, Medeiros-Silva J, Jo H, et al. (2023) Hexamethylene Amiloride Binds the SARS-CoV-2 Envelope Protein at the Protein-Lipid Interface. Protein Science : a Publication of the Protein Society. e4755 |
Yang H, Yuan P, Wu Y, et al. (2023) EMBER multidimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300769120 |
Yang H, Yuan P, Wu Y, et al. (2023) EMBER multi-dimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains. Biorxiv : the Preprint Server For Biology |
Zhang MY, Yang H, Ortiz G, et al. (2022) Covalent labeling of a chromatin reader domain using proximity-reactive cyclic peptides. Chemical Science. 13: 6599-6609 |
Kratochvil HT, Newberry RW, Mensa B, et al. (2021) Spiers Memorial Lecture: Analysis and design of membrane-interactive peptides. Faraday Discussions |
Scott AJ, Niitsu A, Kratochvil HT, et al. (2021) Constructing ion channels from water-soluble α-helical barrels. Nature Chemistry |
Naudin EA, McEwen AG, Tan SK, et al. (2021) Acyl Transfer Catalytic Activity in De Novo Designed Protein with N-Terminus of α-Helix As Oxyanion-Binding Site. Journal of the American Chemical Society |
Boyce JH, Dang B, Ary B, et al. (2020) Platform to Discover Protease-Activated Antibiotics and Application to Siderophore-Antibiotic Conjugates. Journal of the American Chemical Society |