Jihye Yun, Ph.D.

Affiliations: 
2009 Johns Hopkins University, Baltimore, MD 
Area:
Genetics, Medicine and Surgery
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Parents

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Bert Vogelstein grad student 2009 Johns Hopkins
 (Glucose deprivation selects for KRAS and BRAF mutations in colorectal cancer.)
Lewis C. Cantley post-doc Weill Cornell Medical College
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Publications

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Ngo B, Van Riper JM, Cantley LC, et al. (2019) Targeting cancer vulnerabilities with high-dose vitamin C. Nature Reviews. Cancer
Goncalves MD, Lu C, Tutnauer J, et al. (2019) High-fructose corn syrup enhances intestinal tumor growth in mice. Science (New York, N.Y.). 363: 1345-1349
Goncalves M, Lu C, Hartman T, et al. (2019) SAT-LB057 High-Fructose Corn Syrup Enhances Intestinal Tumor Growth in Mice Journal of the Endocrine Society. 3
Shim H, Wu C, Ramsamooj S, et al. (2016) Deletion of the gene Pip4k2c, a novel phosphatidylinositol kinase, results in hyperactivation of the immune system. Proceedings of the National Academy of Sciences of the United States of America
Yun J, Mullarky E, Lu C, et al. (2015) Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science (New York, N.Y.)
Roper J, Sinnamon MJ, Coffee EM, et al. (2014) Combination PI3K/MEK inhibition promotes tumor apoptosis and regression in PIK3CA wild-type, KRAS mutant colorectal cancer. Cancer Letters. 347: 204-11
Parkhitko AA, Priolo C, Coloff JL, et al. (2014) Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide. Molecular Cancer Research : McR. 12: 48-57
Yun J, Kavalier A, Mullarky E, et al. (2014) Abstract 2951: Vitamin C is selectively toxic to cancer cells harboring KRAS or BRAF mutations by targeting GAPDH Cancer Research. 74: 2951-2951
Yun J, Kavalier A, Roper J, et al. (2013) Abstract C60: Vitamin C inhibits the survival and growth of colorectal cancer cells with KRAS or BRAF mutations Cancer Research. 73
Yun J, Poulogiannis G, Brower ET, et al. (2013) The PI3K pathway in colorectal cancers Molecular Pathogenesis of Colorectal Cancer. 157-199
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