Jian Yu
Affiliations: | 2001 | Johns Hopkins University, Baltimore, MD |
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Parents
Sign in to add mentorBert Vogelstein | grad student | 2001 | Johns Hopkins | |
(p53-induced genes and apoptosis.) |
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Publications
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Chen D, Ermine K, Wang YJ, et al. (2023) PUMA/RIP3 mediates chemotherapy response via necroptosis and local immune activation in colorectal cancer. Molecular Cancer Therapeutics |
Tong J, Tan X, Hao S, et al. (2023) Inhibition of multiple CDKs potentiates colon cancer chemotherapy via p73-mediated DR5 induction. Oncogene |
Hao S, Tong J, Jha A, et al. (2022) Synthetical lethality of Werner helicase and mismatch repair deficiency is mediated by p53 and PUMA in colon cancer. Proceedings of the National Academy of Sciences of the United States of America. 119: e2211775119 |
Kuang C, Tong J, Ermine K, et al. (2022) Dual inhibition of BET and HAT/p300 suppresses colorectal cancer via DR5- and p53/PUMA-mediated cell death. Frontiers in Oncology. 12: 1018775 |
Ruan H, Leibowitz BJ, Peng Y, et al. (2022) Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer. Molecular Biomedicine. 3: 10 |
Tong J, Tan X, Song X, et al. (2022) CDK4/6 inhibition suppresses p73 phosphorylation and activates DR5 to potentiate chemotherapy and immune checkpoint blockade. Cancer Research |
Tong J, Tan X, Risnik D, et al. (2021) BET protein degradation triggers DR5-mediated immunogenic cell death to suppress colorectal cancer and potentiate immune checkpoint blockade. Oncogene. 40: 6566-6578 |
Song X, Shen L, Tong J, et al. (2020) Mcl-1 inhibition overcomes intrinsic and acquired regorafenib resistance in colorectal cancer. Theranostics. 10: 8098-8110 |
Ruan H, Leibowitz BJ, Zhang L, et al. (2020) Immunogenic cell death in colon cancer prevention and therapy. Molecular Carcinogenesis |
Dang Y, Zhang Y, Xu L, et al. (2020) PUMA-mediated epithelial cell apoptosis promotes Helicobacter pylori infection-mediated gastritis. Cell Death & Disease. 11: 139 |