Irfan A. Khan, PhD

Affiliations: 
2014-2017 Chemistry State University of New York, Albany, Albany, NY, United States 
Area:
Molecular cell biology, Cancer medicine and Nanotechnology
Website:
http://www.royzenlab.science/
Google:
"https://scholar.google.com/citations?user=v22vQUcAAAAJ&hl=en"
Bio:

I am a Research Scientist in the Department of Chemistry and the RNA Institute at the State University of New York at Albany. I am currently working on development of activatable nanoprobes for in vivo imaging of oncogenes. My current research interests involve collaborative research projects between Bio-conjugate chemistry and cancer biology in order to design, synthesize, and evaluate bioactive small molecules as drugs or biomarkers. A significant part of my research project here at The RNA Institute is devoted to investigation of prodrugs of Doxorubicin and Gemcitabine to find a new class of less toxic cancer inhibitors particularly for breast and pancreatic cancer.

Mean distance: (not calculated yet)
 

Parents

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Syed Hamid Ali grad student 2007-2012 SUNY Buffalo
 (Awesome Mentor)
Shahana Urooj Kazmi grad student 2007-2012 University of Maryland
 (Awesome Mentor, outstanding researcher)
Maksim Royzen post-doc 2014-2017 SUNY Albany
 (Awesome supervisor, real scientist)

Children

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Muhammad Ali grad student 2016-2016 SUNY Albany
BETA: Related publications

Publications

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Uyar TB, Wu K, He M, et al. (2020) Switchable fluorescence of doxorubicin for label-free imaging of bioorthogonal drug release. Chemmedchem
Wu K, He M, Khan I, et al. (2019) Bio-orthogonal chemistry-based method for fluorescent labelling of ribosomal RNA in live mammalian cells. Chemical Communications (Cambridge, England)
Czuban M, Srinivasan S, Yee NA, et al. (2018) Bio-Orthogonal Chemistry and Reloadable Biomaterial Enable Local Activation of Antibiotic Prodrugs and Enhance Treatments against Infections. Acs Central Science. 4: 1624-1632
Khan I, Seebald LM, Robertson NM, et al. (2017) Controlled in-cell activation of RNA therapeutics using bond-cleaving bio-orthogonal chemistry. Chemical Science. 8: 5705-5712
Robertson NM, Yang Y, Khan I, et al. (2017) Single-trigger dual-responsive nanoparticles for controllable and sequential prodrug activation. Nanoscale
Mejia Oneto JM, Khan I, Seebald L, et al. (2016) In Vivo Bioorthogonal Chemistry Enables Local Hydrogel and Systemic Pro-Drug To Treat Soft Tissue Sarcoma. Acs Central Science. 2: 476-82
Khan I, Agris PF, Yigit MV, et al. (2016) In situ activation of a doxorubicin prodrug using imaging-capable nanoparticles. Chemical Communications (Cambridge, England)
Agustin E, Asare Okai PN, Khan I, et al. (2015) A fast click-slow release strategy towards the HPLC-free synthesis of RNA. Chemical Communications (Cambridge, England)
Siddiqui S, Khan I, Zarina S, et al. (2013) Use of the SYBR Green dye for measuring helicase activity. Enzyme and Microbial Technology. 52: 196-8
Khan IA, Siddiqui S, Rehmani S, et al. (2012) Fluoroquinolones inhibit HCV by targeting its helicase. Antiviral Therapy. 17: 467-76
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