Edward P. Harvey
Affiliations: | Dana-Farber Cancer Institute, Boston, MA, United States |
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Publications
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Pinch BJ, Buckley DL, Gleim S, et al. (2021) A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes. Cell Chemical Biology |
Cathcart AM, Bird GH, Wales TE, et al. (2020) Targeting a helix-in-groove interaction between E1 and E2 blocks ubiquitin transfer. Nature Chemical Biology |
Hauseman ZJ, Harvey EP, Newman CE, et al. (2020) Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization. Molecular Cell |
Harvey EP, Hauseman ZJ, Cohen DT, et al. (2020) Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering. Cell Chemical Biology |
Ben-Nun Y, Seo HS, Harvey EP, et al. (2020) Identification of a Structural Determinant for Selective Targeting of HDMX. Structure (London, England : 1993) |
Guerra RM, Bird GH, Harvey EP, et al. (2018) Precision Targeting of BFL-1/A1 and an ATM Co-dependency in Human Cancer. Cell Reports. 24: 3393-3403.e5 |
Harvey EP, Seo HS, Guerra RM, et al. (2018) Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor. Structure (London, England : 1993). 26: 153-160.e4 |
Huhn AJ, Guerra RM, Harvey EP, et al. (2016) Selective Covalent Targeting of Anti-Apoptotic BFL-1 by Cysteine-Reactive Stapled Peptide Inhibitors. Cell Chemical Biology |