Achuth Padmanabhan

Affiliations: 
2005-2012 Biological Sciences University of Maryland, Baltimore County, Baltimore, MD, United States 
 2012-2015 Molecular Biophysics and Biochemistry Yale University, New Haven, CT 
 2016-2019 Molecular and Cellular Biology Baylor College of Medicine, Houston, TX 
 2019- Biological Sciences University of Maryland, Baltimore County, Baltimore, MD, United States 
Area:
Cancer Biology, Protein degradation, Oncogenes, Tumor Suppressors, Assay Development
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"Achuth Padmanabhan"
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Parents

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Charles J. Bieberich grad student 2012 UMBC
 (A MYC-protein kinase a signaling loop regulates MYC in prostate cancer cells.)
Mark W. Hochstrasser post-doc 2012-2015 Yale
 (Proteasome assembly in mammalian cells)
JoAnne Stewart Richards post-doc 2016-2019 Baylor College of Medicine
 (Models and mechanisms in ovarian cancer)
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Publications

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Padmanabhan A, Kaushik M, Niranjan R, et al. (2019) Zinc Oxide nanoparticles induce oxidative and proteotoxic stress in ovarian cancer cells and trigger apoptosis Independent of p53-mutation status. Applied Surface Science. 487: 807-818
Candelaria NR, Padmanabhan A, Stossi F, et al. (2019) VCAM1 is Induced in Ovarian Theca and Stromal Cells in a Mouse Model of Androgen Excess. Endocrinology
Padmanabhan A, Candelaria N, Wong KK, et al. (2018) USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells. Nature Communications. 9: 1270
Padmanabhan A, Candelaria N, Wong K, et al. (2017) Abstract 2579: Identifying pathways that regulate the turnover of gain-of-function p53 mutant proteins in ovarian cancer cells Cancer Research. 77: 2579-2579
Padmanabhan A, Vuong SA, Hochstrasser M. (2016) Assembly of an Evolutionarily Conserved Alternative Proteasome Isoform in Human Cells. Cell Reports. 14: 2962-74
Padmanabhan A, Rao V, De Marzo AM, et al. (2016) Regulating NKX3.1 stability and function: Post-translational modifications and structural determinants. The Prostate. 76: 523-33
Padmanabhan A, Rao V, De Marzo AM, et al. (2016) Regulating NKX3.1 stability and function: Post-translational modifications and structural determinants Prostate
Padmanabhan A. (2014) Targeting Protein Kinase Substrate Docking in Cancers Journal of Glycobiology. 3: 1-1
Padmanabhan A, Li X, Bieberich CJ. (2013) Protein kinase A regulates MYC protein through transcriptional and post-translational mechanisms in a catalytic subunit isoform-specific manner. The Journal of Biological Chemistry. 288: 14158-69
Padmanabhan A, Gosc EB, Bieberich CJ. (2013) Stabilization of the prostate-specific tumor suppressor NKX3.1 by the oncogenic protein kinase Pim-1 in prostate cancer cells. Journal of Cellular Biochemistry. 114: 1050-7
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