H. Lee Sweeney
Affiliations: | 1984 | Physiology and Biophysics | Harvard Medical School, Boston, MA, United States |
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| Radnai L, Young EJ, Kikuti C, et al. (2024) Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors with Broad Therapeutic Potential. Biorxiv : the Preprint Server For Biology |
| Canon L, Kikuti C, Planelles-Herrero VJ, et al. (2023) How myosin VI traps its off-state, is activated and dimerizes. Nature Communications. 14: 6732 |
| Bodine SC, Sinha I, Sweeney HL. (2023) Mechanisms of Skeletal Muscle Atrophy and Molecular Circuitry of Stem Cell Fate in Skeletal Muscle Regeneration and Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 78: 14-18 |
| Russell AJ, DuVall M, Barthel B, et al. (2023) Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy. The Journal of Clinical Investigation |
| Pospich S, Sweeney HL, Houdusse A, et al. (2021) High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife. 10 |
| Hammers DW, Hart CC, Matheny MK, et al. (2021) Filopodia powered by class X myosin promote fusion of mammalian myoblasts. Elife. 10 |
| Hammers DW, Hart CC, Matheny MK, et al. (2020) The D2.mdx mouse as a preclinical model of the skeletal muscle pathology associated with Duchenne muscular dystrophy. Scientific Reports. 10: 14070 |
| Sweeney HL, Houdusse A, Robert-Paganin J. (2020) Myosin Structures. Advances in Experimental Medicine and Biology. 1239: 7-19 |
| Hammers DW, Hart CC, Patsalos A, et al. (2019) Glucocorticoids counteract hypertrophic effects of myostatin inhibition in dystrophic muscle. Jci Insight |
| Robert-Paganin J, Pylypenko O, Kikuti C, et al. (2019) Force Generation by Myosin Motors: A Structural Perspective. Chemical Reviews |