Alex Chia Yu Chang, PhD

Affiliations: 
2012- Cardiovascular Institute Stanford University, Palo Alto, CA 
 2012- M&I - Baxter Laboratory Stanford University, Palo Alto, CA 
Area:
Cardiomyopathy; Telomere; Mitochondrial Dysfunction
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Parents

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Aly Karsan grad student 2006-2012 UBC (Cell Biology Tree)
Helen M. Blau post-doc 2012- Stanford (Neurotree)

Collaborators

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Joseph C. Wu collaborator 2013- Stanford (Physics Tree)
John W. Day collaborator 2014- Stanford (Anthropology Tree)
Ashley Euan collaborator 2014- Stanford (GenetiTree)
Jonathan Seidman collaborator 2014- Harvard (GenetiTree)
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Publications

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Togninalli M, Ho ATV, Madl CM, et al. (2023) Machine learning-based classification of dual fluorescence signals reveals muscle stem cell fate transitions in response to regenerative niche factors. Npj Regenerative Medicine. 8: 4
Yucel N, Chang AC, Day JW, et al. (2020) Author Correction: Humanizing the mdx mouse model of DMD: the long and the short of it. Npj Regenerative Medicine. 5: 25
Yucel N, Chang AC, Day JW, et al. (2018) Humanizing the mdx mouse model of DMD: the long and the short of it. Npj Regenerative Medicine. 3: 4
Rhee S, Chung JI, King DA, et al. (2018) Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease. Nature Communications. 9: 368
Zhang JZ, Termglinchan V, Itzhaki I, et al. (2018) Abstract 217: TBX5 Clover2 /NKX2-5 TagRFP hiPSCs for Simultaneously Isolating Lineage-Specific Cardiovascular Cells Circulation Research. 123
Chang AC, Ong SG, LaGory EL, et al. (2016) Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America
Burridge PW, Li YF, Matsa E, et al. (2016) Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity. Nature Medicine
Chang AC, Garside VC, Fournier M, et al. (2014) A Notch-dependent transcriptional hierarchy promotes mesenchymal transdifferentiation in the cardiac cushion. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 243: 894-905
El-Sehemy A, Chang AC, Azad AK, et al. (2013) Notch activation augments nitric oxide/soluble guanylyl cyclase signaling in immortalized ovarian surface epithelial cells and ovarian cancer cells. Cellular Signalling. 25: 2780-7
Chang AC, Patenaude A, Lu K, et al. (2013) Notch-dependent regulation of the ischemic vasodilatory response--brief report. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 510-2
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