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Marcos M. Sotomayor

Affiliations: 
Chemistry and Biochemistry Ohio State University, Columbus, Columbus, OH 
Area:
Mechanotransduction - Cellular Adhesion - Structural Biology - Molecular Dynamics Simulations - Protein Biochemistry and Biophysics
Website:
http://chemistry.osu.edu/faculty/sotomayor
Google:
"Marcos M. Sotomayor"
Bio:

https://research.chemistry.ohio-state.edu/sotomayor/

Mean distance: 8.36
 
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Parents

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Klaus Schulten grad student 2007 UIUC
 (Life under tension : computational studies of proteins involved in mechanotransduction)
David P. Corey post-doc 2013 Harvard Medical School
Rachelle Gaudet post-doc 2008-2013 Harvard
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Publications

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Tamilselvan E, Sotomayor M. (2024) CELSR1, a core planar cell polarity protein, features a weakly adhesive and flexible cadherin ectodomain. Structure (London, England : 1993)
Zheng W, Rawson S, Shen Z, et al. (2023) TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels. Neuron
Giese APJ, Weng WH, Kindt KS, et al. (2023) Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels. Biorxiv : the Preprint Server For Biology
Ivanchenko MV, Hathaway DM, Klein AJ, et al. (2023) Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F. Nature Communications. 14: 2400
Nisler CR, Narui Y, Scheib E, et al. (2023) Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation. Molecular Biology and Evolution. 40
Neel BL, Nisler CR, Walujkar S, et al. (2022) Elastic versus Brittle Mechanical Responses Predicted for Dimeric Cadherin Complexes. Biophysical Journal
Gray ME, Johnson ZR, Modak D, et al. (2021) Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent. Plos Biology. 19: e3001463
Ahmed T, Nisler CR, Fluck EC, et al. (2021) Structure of the ancient TRPY1 channel from Saccharomyces cerevisiae reveals mechanisms of modulation by lipids and calcium. Structure (London, England : 1993)
Gray ME, Sotomayor M. (2021) Crystal structure of the nonclassical cadherin-17 N-terminus and implications for its adhesive binding mechanism. Acta Crystallographica. Section F, Structural Biology Communications. 77: 85-94
Choudhary D, Narui Y, Neel BL, et al. (2020) Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception. Proceedings of the National Academy of Sciences of the United States of America
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