Eric M. Phizicky

Affiliations: 
Biochemistry and Biophysics University of Rochester Medical Center, Rochester, NY, United States 
Area:
tRNA Biogenesis, Function and Quality Control
Website:
http://www.urmc.rochester.edu/people/20653606-eric-m-phizicky
Google:
"Eric M. Phizicky"
Bio:

http://www.urmc.rochester.edu/labs/Phizicky-Lab/

Mean distance: 9.38
 
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Parents

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Jeffrey W. Roberts grad student 1983 Cornell
 (Regulation to the proteolytic activity of Escherichia coli RecA protein)
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Publications

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Funk HM, DiVita DJ, Sizemore HE, et al. (2022) Identification of a Trm732 Motif Required for 2'--methylation of the tRNA Anticodon Loop by Trm7. Acs Omega. 7: 13667-13675
Han L, Marcus E, Phizicky EM. (2021) A semi-quantitative pull-down assay to study tRNA substrate specificity of modification enzymes. Methods in Enzymology. 658: 359-377
De Zoysa T, Phizicky EM. (2020) Hypomodified tRNA in evolutionarily distant yeasts can trigger rapid tRNA decay to activate the general amino acid control response, but with different consequences. Plos Genetics. 16: e1008893
Payea MJ, Hauke AC, De Zoysa T, et al. (2019) Mutations in the anticodon stem of tRNA cause accumulation and Met22-dependent decay of pre-tRNA in yeast. Rna (New York, N.Y.)
Ramos J, Han L, Li Y, et al. (2019) Formation of tRNA wobble inosine in humans is disrupted by a millennia-old mutation causing intellectual disability. Molecular and Cellular Biology
Shaheen R, Tasak M, Maddirevula S, et al. (2019) PUS7 mutations impair pseudouridylation in humans and cause intellectual disability and microcephaly. Human Genetics
Han L, Phizicky EM. (2018) A rationale for tRNA modification circuits in the anticodon loop. Rna (New York, N.Y.)
Zimmerman SM, Kon Y, Hauke AC, et al. (2018) Conditional accumulation of toxic tRNAs to cause amino acid misincorporation. Nucleic Acids Research
Han L, Guy MP, Kon Y, et al. (2018) Lack of 2'-O-methylation in the tRNA anticodon loop of two phylogenetically distant yeast species activates the general amino acid control pathway. Plos Genetics. 14: e1007288
Payea MJ, Sloma MF, Kon Y, et al. (2017) Widespread temperature sensitivity and tRNA decay due to mutations in a yeast tRNA. Rna (New York, N.Y.)
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