Eric M. Phizicky
Affiliations: | Biochemistry and Biophysics | University of Rochester Medical Center, Rochester, NY, United States |
Area:
tRNA Biogenesis, Function and Quality ControlWebsite:
http://www.urmc.rochester.edu/people/20653606-eric-m-phizickyGoogle:
"Eric M. Phizicky"Bio:
http://www.urmc.rochester.edu/labs/Phizicky-Lab/
Mean distance: 9.38 | S | N | B | C | P |
Parents
Sign in to add mentorJeffrey W. Roberts | grad student | 1983 | Cornell | |
(Regulation to the proteolytic activity of Escherichia coli RecA protein) |
Children
Sign in to add traineeJane E. Jackman | post-doc | 2007 | University of Rochester Medical Center |
BETA: Related publications
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Publications
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Funk HM, DiVita DJ, Sizemore HE, et al. (2022) Identification of a Trm732 Motif Required for 2'--methylation of the tRNA Anticodon Loop by Trm7. Acs Omega. 7: 13667-13675 |
Han L, Marcus E, Phizicky EM. (2021) A semi-quantitative pull-down assay to study tRNA substrate specificity of modification enzymes. Methods in Enzymology. 658: 359-377 |
De Zoysa T, Phizicky EM. (2020) Hypomodified tRNA in evolutionarily distant yeasts can trigger rapid tRNA decay to activate the general amino acid control response, but with different consequences. Plos Genetics. 16: e1008893 |
Payea MJ, Hauke AC, De Zoysa T, et al. (2019) Mutations in the anticodon stem of tRNA cause accumulation and Met22-dependent decay of pre-tRNA in yeast. Rna (New York, N.Y.) |
Ramos J, Han L, Li Y, et al. (2019) Formation of tRNA wobble inosine in humans is disrupted by a millennia-old mutation causing intellectual disability. Molecular and Cellular Biology |
Shaheen R, Tasak M, Maddirevula S, et al. (2019) PUS7 mutations impair pseudouridylation in humans and cause intellectual disability and microcephaly. Human Genetics |
Han L, Phizicky EM. (2018) A rationale for tRNA modification circuits in the anticodon loop. Rna (New York, N.Y.) |
Zimmerman SM, Kon Y, Hauke AC, et al. (2018) Conditional accumulation of toxic tRNAs to cause amino acid misincorporation. Nucleic Acids Research |
Han L, Guy MP, Kon Y, et al. (2018) Lack of 2'-O-methylation in the tRNA anticodon loop of two phylogenetically distant yeast species activates the general amino acid control pathway. Plos Genetics. 14: e1007288 |
Payea MJ, Sloma MF, Kon Y, et al. (2017) Widespread temperature sensitivity and tRNA decay due to mutations in a yeast tRNA. Rna (New York, N.Y.) |