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Bernard L Trumpower, Ph.D.

Affiliations: 
Biochemistry Geisel School of Medicine at Dartmouth, Hanover, NH, United States 
Area:
Cytochromes
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"Bernard Trumpower"
Mean distance: 15925.2
 
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Children

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Mark E Schmitt grad student 1985-1990 Dartmouth Medical School
Fred A. Dick grad student 1993-1998 Dartmouth Medical School (Cell Biology Tree)
Joseph D. Beckmann post-doc 1984-1987 Dartmouth Medical School

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Publications

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Hughes LM, Lanteri CA, O'Neil MT, et al. (2011) Design of anti-parasitic and anti-fungal hydroxy-naphthoquinones that are less susceptible to drug resistance. Molecular and Biochemical Parasitology. 177: 12-9
Conte L, Trumpower BL, Zara V. (2011) Bcs1p can rescue a large and productive cytochrome bc(1) complex assembly intermediate in the inner membrane of yeast mitochondria. Biochimica Et Biophysica Acta. 1813: 91-101
Castellani M, Covian R, Kleinschroth T, et al. (2010) Direct demonstration of half-of-the-sites reactivity in the dimeric cytochrome bc1 complex: enzyme with one inactive monomer is fully active but unable to activate the second ubiquinol oxidation site in response to ligand binding at the ubiquinone reduction site. The Journal of Biological Chemistry. 285: 502-10
Hughes LM, Covian R, Gribble GW, et al. (2010) Probing binding determinants in center P of the cytochrome bc(1) complex using novel hydroxy-naphthoquinones. Biochimica Et Biophysica Acta. 1797: 38-43
Castellani M, Kleinschroth T, Covian R, et al. (2010) Heterodimeric bc1 complex from Paracoccus denitrificans: A validation of the half-of-the-sites mechanism Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1797: 112-113
Rottenberg H, Covian R, Trumpower BL. (2009) Membrane potential greatly enhances superoxide generation by the cytochrome bc1 complex reconstituted into phospholipid vesicles. The Journal of Biological Chemistry. 284: 19203-10
Ding MG, Butler CA, Saracco SA, et al. (2009) Chapter 27 An improved method for introducing point mutations into the mitochondrial cytochrome B gene to facilitate studying the role of cytochrome B in the formation of reactive oxygen species. Methods in Enzymology. 456: 491-506
Covian R, Trumpower BL. (2009) The rate-limiting step in the cytochrome bc1 complex (Ubiquinol-Cytochrome c Oxidoreductase) is not changed by inhibition of cytochrome b-dependent deprotonation: implications for the mechanism of ubiquinol oxidation at center P of the bc1 complex. The Journal of Biological Chemistry. 284: 14359-67
Zara V, Conte L, Trumpower BL. (2009) Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane. The Febs Journal. 276: 1900-14
Ding MG, di Rago JP, Trumpower BL. (2009) Combining Inhibitor Resistance-conferring Mutations in Cytochrome b Creates Conditional Synthetic Lethality in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 284: 8478-85
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