J. Patrick Loria
Affiliations: | Molecular Biophysics and Biochemistry | Yale University, New Haven, CT |
Area:
General Biophysics, BiochemistryWebsite:
https://chem.yale.edu/people/j-patrick-loriaGoogle:
"Patrick Loria"Bio:
http://xbeams.chem.yale.edu/~loria
Mean distance: 9.14
Parents
Sign in to add mentorThomas L. Nowak | grad student | 1997 | Notre Dame | |
(Active site structure and conformational changes in yeast pyruvate kinase) | ||||
Arthur G. Palmer, III | post-doc | 1997-2001 | Columbia |
Children
Sign in to add traineeGregory Manley | grad student | Yale | |
Roger B. Cole | grad student | 2004 | Yale |
Dagny L. Ulrich | grad student | 2005 | Yale |
Michelle L. Gill | grad student | 2006 | Yale |
Thusitha B. Jayasundera | grad student | 2009 | Yale |
James M. Lipchock | grad student | 2010 | Yale |
yan wang | grad student | 2010 | Yale (Neurotree) |
Rebecca B. Berlow | grad student | 2011 | Yale |
Eric D. Watt | grad student | 2012 | Yale |
Gennady Khirich | grad student | 2014 | Yale |
Sean K. Whittier | grad student | 2014 | Yale |
Nicolas Doucet | post-doc | Yale | |
James G. Kempf | post-doc | Yale | |
Evgueni Kovrigin | post-doc | Yale | |
George P. Lisi | post-doc | Yale | |
Elizabeth M. Moscato-Goodpaster | post-doc | Yale | |
Monalisa Swain | post-doc | Yale |
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Publications
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Yehorova D, Alansson N, Shen R, et al. (2025) Conformational Dynamics and Catalytic Backups in a Hyper-Thermostable Engineered Archaeal Protein Tyrosine Phosphatase. Biorxiv : the Preprint Server For Biology |
Manu VS, Melacini G, Kovrigin EL, et al. (2025) Unbiased clustering of residues undergoing synchronous motions in proteins using NMR spin relaxation data. Biophysical Chemistry. 107411 |
Zavala E, Dansereau S, Burke MJ, et al. (2024) A salt bridge of the C-terminal carboxyl group regulates PHPT1 substrate affinity and catalytic activity. Protein Science : a Publication of the Protein Society. 33: e5009 |
Maschietto F, Morzan UN, Tofoleanu F, et al. (2023) Turning up the heat mimics allosteric signaling in imidazole-glycerol phosphate synthase. Nature Communications. 14: 2239 |
Shen R, Crean RM, Olsen KJ, et al. (2022) Insights into the importance of WPD-loop sequence for activity and structure in protein tyrosine phosphatases. Chemical Science. 13: 13524-13540 |
Maschietto F, Zavala E, Allen B, et al. (2022) MptpA Kinetics Enhanced by Allosteric Control of an Active Conformation. Journal of Molecular Biology. 167540 |
Pinkston J, Jo J, Olsen KJ, et al. (2021) Significant Loop Motions in the SsoPTP Protein Tyrosine Phosphatase Allow for Dual General Acid Functionality. Biochemistry |
Medeiros Almeida V, Chaudhuri A, Cangussu Cardoso MV, et al. (2021) Role of a high centrality residue in protein dynamics and thermal stability. Journal of Structural Biology. 213: 107773 |
Berk JM, Lim C, Ronau JA, et al. (2020) A deubiquitylase with an unusually high-affinity ubiquitin-binding domain from the scrub typhus pathogen Orientia tsutsugamushi. Nature Communications. 11: 2343 |
Beaumont V, Reiss K, Qu Z, et al. (2020) The allosteric impact of the variable insert loop in Vaccinia H1-related (VHR) phosphatase. Biochemistry |