Xiaochun Chen

Affiliations: 
University of Maryland School of Medicine, Baltimore, MD, United States 
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"Xiaochun Chen"
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Publications

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Chen X, Chen J, Yan Y, et al. (2018) Quorum sensing inhibitors from marine bacteria Oceanobacillus sp. XC22919. Natural Product Research. 1-5
Moses BS, Fox JM, Chen X, et al. (2017) Abstract 2023: Artemisinins enhanced the antileukemic efficacy of BCL2 inhibitors Cancer Research. 77: 2023-2023
Fox JM, Moynihan JR, Mott BT, et al. (2016) Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs. Oncotarget
Kishor C, Arya T, Reddi R, et al. (2013) Identification, biochemical and structural evaluation of species-specific inhibitors against type I methionine aminopeptidases. Journal of Medicinal Chemistry. 56: 5295-305
Zhang F, Bhat S, Gabelli SB, et al. (2013) Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells Journal of Medicinal Chemistry. 56: 3996-4016
Zhang P, Yang X, Zhang F, et al. (2013) Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1. Bioorganic & Medicinal Chemistry. 21: 2600-17
Woodard LE, Chang W, Chen X, et al. (2009) Malaria-infected mice live until at least day 30 after a new monomeric trioxane combined with mefloquine are administered together in a single low oral dose Journal of Medicinal Chemistry. 52: 7458-7462
Chen X, Xie S, Bhat S, et al. (2009) Fumagillin and fumarranol interact with P. falciparum methionine aminopeptidase 2 and inhibit malaria parasite growth in vitro and in vivo. Chemistry & Biology. 16: 193-202
Rosenthal AS, Chen X, Liu JO, et al. (2009) Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells. Journal of Medicinal Chemistry. 52: 1198-203
Hu XV, Chen X, Han KC, et al. (2007) Kinetic and mutational studies of the number of interacting divalent cations required by bacterial and human methionine aminopeptidases. Biochemistry. 46: 12833-43
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