Ralph A. Cacho
Affiliations: | University of Washington, Seattle, Seattle, WA |
Area:
biochemistry, protein design, enzymology, natural product biosynthesisGoogle:
"Ralph Cacho"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Yi Tang | grad student | 2010-2015 | |
| David Baker | post-doc | 2015- | University of Washington |
BETA: Related publications
See more...
Publications
|
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
| Grandner JM, Cacho RA, Tang Y, et al. (2016) Mechanism of the P450-Catalyzed Oxidative Cyclization in the Biosynthesis of Griseofulvin. Acs Catalysis. 6: 4506-4511 |
| Zhang J, Liu N, Cacho RA, et al. (2016) Structural basis of nonribosomal peptide macrocyclization in fungi. Nature Chemical Biology |
| Cacho RA, Tang Y. (2016) Reconstitution of Fungal Nonribosomal Peptide Synthetases in Yeast and In Vitro. Methods in Molecular Biology (Clifton, N.J.). 1401: 103-19 |
| Cacho RA, Thuss J, Xu W, et al. (2015) Understanding Programming of Fungal Iterative Polyketide Synthases: the Biochemical Basis for Regioselectivity by the Methyltransferase Domain in the Lovastatin Megasynthase. Journal of the American Chemical Society |
| Tang MC, Lin HC, Li D, et al. (2015) Discovery of Unclustered Fungal Indole Diterpene Biosynthetic Pathways through Combinatorial Pathway Reassembly in Engineered Yeast. Journal of the American Chemical Society |
| Zou Y, Zhan Z, Li D, et al. (2015) Tandem prenyltransferases catalyze isoprenoid elongation and complexity generation in biosynthesis of quinolone alkaloids. Journal of the American Chemical Society. 137: 4980-3 |
| Cacho RA, Tang Y, Chooi YH. (2014) Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi. Frontiers in Microbiology. 5: 774 |
| Chooi YH, Hong YJ, Cacho RA, et al. (2013) A cytochrome P450 serves as an unexpected terpene cyclase during fungal meroterpenoid biosynthesis. Journal of the American Chemical Society. 135: 16805-8 |
| Cacho RA, Chooi YH, Zhou H, et al. (2013) Complexity generation in fungal polyketide biosynthesis: a spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin. Acs Chemical Biology. 8: 2322-30 |
| Yin WB, Chooi YH, Smith AR, et al. (2013) Discovery of cryptic polyketide metabolites from dermatophytes using heterologous expression in Aspergillus nidulans. Acs Synthetic Biology. 2: 629-34 |