Fan Wang
Affiliations: | 2012 | Rice University, Houston, TX |
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Parents
Sign in to add mentor| Laura Segatori | grad student | 2012 | Rice University | |
| (Modulating protein homeostasis to ameliorate lysosomal storage disorders.) | ||||
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Publications
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| Song W, Wang F, Lotfi P, et al. (2014) 2-Hydroxypropyl-β-cyclodextrin promotes transcription factor EB-mediated activation of autophagy: implications for therapy. The Journal of Biological Chemistry. 289: 10211-22 |
| Wang F, Segatori L. (2013) Remodeling the proteostasis network to rescue glucocerebrosidase variants by inhibiting ER-associated degradation and enhancing ER folding. Plos One. 8: e61418 |
| Song W, Wang F, Savini M, et al. (2013) TFEB regulates lysosomal proteostasis. Human Molecular Genetics. 22: 1994-2009 |
| Mathieu JM, Wang F, Segatori L, et al. (2012) Increased resistance to oxysterol cytotoxicity in fibroblasts transfected with a lysosomally targeted Chromobacterium oxidase. Biotechnology and Bioengineering. 109: 2409-15 |
| Wang F, Song W, Brancati G, et al. (2011) Inhibition of endoplasmic reticulum-associated degradation rescues native folding in loss of function protein misfolding diseases. The Journal of Biological Chemistry. 286: 43454-64 |
| Wang F, Chou A, Segatori L. (2011) Lacidipine remodels protein folding and Ca 2+ homeostasis in Gaucher's disease fibroblasts: a mechanism to rescue mutant glucocerebrosidase. Chemistry & Biology. 18: 766-76 |
| Wang F, Agnello G, Sotolongo N, et al. (2011) Ca2+ homeostasis modulation enhances the amenability of L444P glucosylcerebrosidase to proteostasis regulation in patient-derived fibroblasts. Acs Chemical Biology. 6: 158-68 |