SHUAI Liu
Affiliations: | University of Massachusetts, Boston, Boston, MA |
Area:
Organic Chemistry, Medicinal ChemistryGoogle:
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Publications
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| Muthengi A, Wimalasena VK, Yosief HO, et al. (2021) Development of Dimethylisoxazole-Attached Imidazo[1,2-]pyridines as Potent and Selective CBP/P300 Inhibitors. Journal of Medicinal Chemistry |
| Zhou D, Hayashi T, Jean M, et al. (2020) Inhibition of Polo-like kinase 1 (PLK1) facilitates the elimination of HIV-1 viral reservoirs in CD4 T cells ex vivo. Science Advances. 6: eaba1941 |
| Timme N, Han Y, Liu S, et al. (2019) Small-Molecule Dual PLK1 and BRD4 Inhibitors are Active Against Preclinical Models of Pediatric Solid Tumors. Translational Oncology. 13: 221-232 |
| Kong W, Hayashi T, Fiches G, et al. (2019) Diversified Application of Barcoded PLATO (PLATO-BC) Platform for Identification of Protein Interactions. Genomics, Proteomics & Bioinformatics |
| Gui B, Gui F, Takai T, et al. (2019) Selective targeting of PARP-2 inhibits androgen receptor signaling and prostate cancer growth through disruption of FOXA1 function. Proceedings of the National Academy of Sciences of the United States of America |
| Liu S, Yosief HO, Dai L, et al. (2018) Structure-guided Design and Development of Potent and Selective Dual Bromodomain 4 (BRD4)/Polo-like Kinase 1 (PLK1) Inhibitors. Journal of Medicinal Chemistry |
| Timme N, Liu S, Yosief H, et al. (2018) Abstract 2624: Dual PLK1 and BRD4 inhibition has synergistic therapeutic effects against high-risk rhabdomyosarcoma Cancer Research. 78: 2624-2624 |
| Huang H, Liu S, Jean M, et al. (2017) A Novel Bromodomain Inhibitor Reverses HIV-1 Latency through Specific Binding with BRD4 to Promote Tat and P-TEFb Association. Frontiers in Microbiology. 8: 1035 |
| Koblan LW, Buckley DL, Ott CJ, et al. (2016) Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET-BRET. Chemmedchem |
| Zhang X, Pham K, Liu S, et al. (2016) Stereoselective synthesis of fused tetrahydroquinazolines through one-pot double [3 + 2] dipolar cycloadditions followed by [5 + 1] annulation. Beilstein Journal of Organic Chemistry. 12: 2204-2210 |