Jeanette L Bertron
Affiliations: | 2016-2020 | Chemistry | Vanderbilt University, Nashville, TN |
| 2020- | University of California, San Francisco, San Francisco, CA |
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| Bertron JL, Duvernay MT, Mitchell SG, et al. (2021) Discovery and Optimization of a Novel Series of Competitive and Central Nervous System-Penetrant Protease-Activated Receptor 4 (PAR4) Inhibitors. Acs Chemical Neuroscience |
| Fulton MG, Bertron JL, Reed CW, et al. (2019) Formal Total Synthesis of Pericoannosin A. The Journal of Organic Chemistry |
| Engers DW, Melancon BJ, Gregro AR, et al. (2019) VU6005806/AZN-00016130, an advanced M positive allosteric modulator (PAM) profiled as a potential preclinical development candidate. Bioorganic & Medicinal Chemistry Letters |
| Bertron JL, Cho HP, Garcia-Barrantes PM, et al. (2018) The discovery of VU0486846: steep SAR from a series of M PAMs based on a novel benzomorpholine core. Bioorganic & Medicinal Chemistry Letters |
| Rook JM, Bertron JL, Cho HP, et al. (2018) A novel M1 PAM VU0486846 exerts efficacy in cognition models without displaying agonist activity or cholinergic toxicity. Acs Chemical Neuroscience |
| Tarr JC, Wood MR, Noetzel MJ, et al. (2017) Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and in vivo characterization of a series of 3-aminoazetidine-derived amides. Bioorganic & Medicinal Chemistry Letters |
| Bertron JL, Ennis EA, Tarr CJ, et al. (2016) Optimization of the choline transporter (CHT) inhibitor ML352: Development of VU6001221, an improved in vivo tool compound. Bioorganic & Medicinal Chemistry Letters |