Joseph Edgar Darling
Affiliations: | 2010-2015 | Chemistry | Syracuse University, Syracuse, NY, United States |
2015-2019 | National Institutes of Health, Bethesda, MD | ||
2019-2021 | Frederick National Laboratory |
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Publications
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McGovern-Gooch KR, Rodrigues T, Darling JE, et al. (2016) Ghrelin octanoylation is completely stabilized in biological samples by alkyl fluorophosphonates. Endocrinology. en20161657 |
Wellman MK, Patterson ZR, MacKay H, et al. (2015) Novel Regulator of Acylated Ghrelin, CF801, Reduces Weight Gain, Rebound Feeding after a Fast, and Adiposity in Mice. Frontiers in Endocrinology. 6: 144 |
McGovern KR, Darling JE, Hougland JL. (2015) Progress in Small Molecule and Biologic Therapeutics Targeting Ghrelin Signaling. Mini Reviews in Medicinal Chemistry |
Zhao F, Darling JE, Gibbs RA, et al. (2015) A new class of ghrelin O-acyltransferase inhibitors incorporating triazole-linked lipid mimetic groups. Bioorganic & Medicinal Chemistry Letters. 25: 2800-3 |
Darling JE, Zhao F, Loftus RJ, et al. (2015) Structure-activity analysis of human ghrelin O-acyltransferase reveals chemical determinants of ghrelin selectivity and acyl group recognition. Biochemistry. 54: 1100-10 |
Darling JE, Prybolsky EP, Sieburg M, et al. (2013) A fluorescent peptide substrate facilitates investigation of ghrelin recognition and acylation by ghrelin O-acyltransferase. Analytical Biochemistry. 437: 68-76 |