Chandravel Krishnasamy

2003-2009

Umesh R. Desai	grad student	2003-2009	VCU
(PhD: Molecular Modeling Studies on Heparin and Heparin Mimetics Interacting With Proteins)

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Mosier PD, Krishnasamy C, Kellogg GE, et al. (2012) On the specificity of heparin/heparan sulfate binding to proteins. Anion-binding sites on antithrombin and thrombin are fundamentally different. Plos One. 7: e48632
Henry BL, Connell J, Liang A, et al. (2009) Interaction of antithrombin with sulfated, low molecular weight lignins: opportunities for potent, selective modulation of antithrombin function. The Journal of Biological Chemistry. 284: 20897-908
Raghuraman A, Liang A, Krishnasamy C, et al. (2009) On designing non-saccharide, allosteric activators of antithrombin. European Journal of Medicinal Chemistry. 44: 2626-31
Krishnasamy C, Raghuraman A, Kier LB, et al. (2008) Application of molecular connectivity and electro-topological indices in quantitative structure-activity analysis of pyrazole derivatives as inhibitors of factor Xa and thrombin. Chemistry & Biodiversity. 5: 2609-20
Monien BH, Krishnasamy C, Olson ST, et al. (2005) Importance of tryptophan 49 of antithrombin in heparin binding and conformational activation. Biochemistry. 44: 11660-8