Rio Boothello

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2009-2014 Virginia Commonwealth University, Richmond, VA, United States 
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"Rio Boothello"
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Umesh R. Desai grad student 2009-2014 VCU
 (PhD: Studies on Rationally Designed, Allosteric Coagulation Inhibitors)
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Publications

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Morla S, Ravikumar O, O'Hara C, et al. (2023) Designing Synthetic, Sulfated Glycosaminoglycan Mimetics That Are Orally Bioavailable and Exhibiting Anticancer Activity. Journal of Medicinal Chemistry
Boothello RS, Sankaranarayanan NV, Sistla JC, et al. (2022) Glycan Modulation of Insulin-like Growth Factor-1 Receptor. Angewandte Chemie (International Ed. in English)
Boothello RS, Desai U. (2022) Thermodynamic Affinity and Nature of Forces Defining Glycosaminoglycan-Protein Systems Using Fluorescence Spectroscopy. Methods in Molecular Biology (Clifton, N.J.). 2303: 259-278
Pingali P, Wu YJ, Boothello R, et al. (2021) High dose acetaminophen inhibits STAT3 and has free radical independent anti-cancer stem cell activity. Neoplasia (New York, N.Y.). 23: 348-359
Kalita M, Chua JS, Boothello RS, et al. (2020) Visualizing antithrombin-binding 3--sulfated heparan sulfate motifs on cell surfaces. Chemical Communications (Cambridge, England)
Boothello RS, Sankaranarayanan NV, Afosah DK, et al. (2020) Studies on fragment-based design of allosteric inhibitors of human factor XIa. Bioorganic & Medicinal Chemistry. 28: 115762
Boothello RS, Sankaranarayanan NV, Afosah DK, et al. (2020) Studies on fragment-based design of allosteric inhibitors of human factor XIa. Bioorganic & Medicinal Chemistry. 28: 115762
Omar AM, El-Araby ME, Abdelghany TM, et al. (2020) Introducing of potent cytotoxic novel 2-(aroylamino)cinnamamide derivatives against colon cancer mediated by dual apoptotic signal activation and oxidative stress. Bioorganic Chemistry. 101: 103953
Sharon C, Boothello R, Vera A, et al. (2019) Abstract 4667: A synergistic combination strategy for optimal inhibition of colon cancer stem cells: Simultaneous inhibition of Insulin-like growth factor-1 receptor-AKT-mammalian target of rapamycin axis and the mevalonate-isoprenoid biosynthetic pathway Cancer Research
Boothello RS, Patel NJ, Sharon C, et al. (2018) A Unique Non-Saccharide Mimetic of Heparin Hexasaccharide Inhibits Colon Cancer Stem Cells via p38 MAP Kinase Activation. Molecular Cancer Therapeutics
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