☰ Chemistry Tree

Joseph E. Wedekind, Ph. D.

Affiliations:

Biochemistry

University of Rochester, Rochester, NY

Area:

x-ray crystallography, ncRNA structure, APOBEC3G

Website:

http://www.urmc.rochester.edu/people/23504899-joseph-e-wedekind

Google:

"Joseph Wedekind"

Mean distance: 8.86

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Cross-listing: Crystallography Tree

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Parents

Ivan Rayment	grad student	1995	UW Madison
David Bruce McKay	post-doc	1995-1999	Stanford University Medical Center

Children

Kefang Xie	grad student	2005	Rochester
Franz Gruswitz	grad student	2006	Rochester
Celeste MacElrevey	grad student	2002-2007	University of Rochester Medical Center
Geoffrey M. Lippa	grad student	2007-2013	University of Rochester Medical Center

Collaborators

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Publications

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Schroeder GM, Kiliushik D, Jenkins JL, et al. (2023) Structure and function analysis of a type III preQ-I riboswitch from E. coli reveals direct metabolite-sensing by the Shine-Dalgarno sequence. The Journal of Biological Chemistry. 105208
Kretsch RC, Andersen ES, Bujnicki JM, et al. (2023) RNA target highlights in CASP15: Evaluation of predicted models by structure providers. Proteins
Schroeder GM, Akinyemi O, Malik J, et al. (2023) A riboswitch separated from its ribosome-binding site still regulates translation. Nucleic Acids Research
Schroeder GM, Cavender CE, Blau ME, et al. (2022) A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control. Nature Communications. 13: 199
Srivastava Y, Bonn-Breach R, Chavali SS, et al. (2021) Affinity and Structural Analysis of the U1A RNA Recognition Motif with Engineered Methionines to Improve Experimental Phasing. Crystals. 11
Chavali SS, Mali SM, Jenkins JL, et al. (2020) Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors. The Journal of Biological Chemistry. 295: 16470-16486
Chavali SS, Cavender CE, Mathews DH, et al. (2020) Arginine Forks Are a Widespread Motif to Recognize Phosphate Backbones and Guanine Nucleobases in the RNA Major Groove. Journal of the American Chemical Society
Chavali SS, Mali SM, Jenkins JL, et al. (2020) Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors. The Journal of Biological Chemistry
Schroeder GM, Dutta D, Cavender CE, et al. (2020) Analysis of a preQ1-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation. Nucleic Acids Research
Bonn-Breach R, Gu Y, Jenkins J, et al. (2019) Structure of Sonic Hedgehog protein in complex with zinc(II) and magnesium(II) reveals ion-coordination plasticity relevant to peptide drug design. Acta Crystallographica. Section D, Structural Biology. 75: 969-979

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