Richard C. Holz, Ph.D.

Affiliations: 
Chemistry Utah State U., Loyola U. Chicago, Marquette U. 
Area:
Bioinorganic Chemistry
Website:
http://www.marquette.edu/about/leadership/artssciences.shtml
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"Richard Holz"
Bio:

Dr. Richard C. Holz is the Dean of the Klingler College of Arts and Sciences.

Prior to joining Marquette, Dr. Holz was a faculty member for seven years in the Department of Chemistry and Biochemistry at Loyola University Chicago. During his term at Loyola, he served as Associate Dean for Resources and Planning in the College of Arts and Sciences (2011-2013) and as Department Chairman of Chemistry and Biochemistry (2006-2011). He was an American Council on Education Fellow (Class of 2010-2011).

Dr. Holz has a B.S. degree from Bemidji State University, M.S. degree from the University of Minnesota-Duluth and Ph.D. degree from the Pennsylvania State University, all in Chemistry. He was an NIH Postdoctoral Research Fellow at the University of Minnesota from 1989-1992 and a faculty member at Utah State University from 1992-2006.

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Parents

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William DeW. Horrocks grad student 1989 Penn State
Lawrence Que post-doc 1989-1992 UMN

Collaborators

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Dali Liu collaborator
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Publications

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Catlin DS, Yang X, Bennett B, et al. (2020) Structural basis for the hydrolytic dehalogenation of the fungicide chlorothalonil. The Journal of Biological Chemistry
Nocek B, Reidl C, Starus A, et al. (2017) Structural Evidence for a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism. Biochemistry
Stein N, Gumataotao N, Hajnas N, et al. (2017) Multiple States of Nitrile Hydratase from Rhodococcus equi TG328-2: Structural and Mechanistic Insights from EPR and DFT Studies. Biochemistry
Martinez S, Wu R, Krzywda K, et al. (2015) Analyzing the catalytic role of active site residues in the Fe-type nitrile hydratase from Comamonas testosteroni Ni1. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 20: 885-94
Martinez S, Wu R, Sanishvili R, et al. (2014) The active site sulfenic acid ligand in nitrile hydratases can function as a nucleophile. Journal of the American Chemical Society. 136: 1186-9
McGregor WC, Gillner DM, Swierczek SI, et al. (2013) Identification of a Histidine Metal Ligand in the argE-Encoded N-Acetyl-L-Ornithine Deacetylase from Escherichia coli. Springerplus. 2: 482
Gumataotao N, Kuhn ML, Hajnas N, et al. (2013) Identification of an active site-bound nitrile hydratase intermediate through single turnover stopped-flow spectroscopy. The Journal of Biological Chemistry. 288: 15532-6
Gillner DM, Becker DP, Holz RC. (2013) Lysine biosynthesis in bacteria: a metallodesuccinylase as a potential antimicrobial target. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 18: 155-63
Kuhn ML, Martinez S, Gumataotao N, et al. (2012) The Fe-type nitrile hydratase from Comamonas testosteroni Ni1 does not require an activator accessory protein for expression in Escherichia coli. Biochemical and Biophysical Research Communications. 424: 365-70
Tao Y, Shokes JE, McGregor WC, et al. (2012) Structural characterization of Zn(II)-, Co(II)-, and Mn(II)-loaded forms of the argE-encoded N-acetyl-L-ornithine deacetylase from Escherichia coli. Journal of Inorganic Biochemistry. 111: 157-63
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