Martin A Fascione
Affiliations: | University of York, UK |
Area:
chemical biology, glycoscienceGoogle:
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Publications
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Keenan T, Spears RJ, Akkad S, et al. (2021) A Tale of Two Bioconjugations: pH Controlled Divergent Reactivity of Protein α-oxo-Aldehydes in Competing α-oxo-Mannich and Catalyst-Free Aldol Ligations. Acs Chemical Biology. 16: 2387-2400 |
Keenan T, Parmeggiani F, Malassis J, et al. (2020) Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides. Cell Chemical Biology |
Brabham RL, Keenan T, Husken A, et al. (2020) Rapid sodium periodate cleavage of an unnatural amino acid enables unmasking of a highly reactive α-oxo aldehyde for protein bioconjugation. Organic & Biomolecular Chemistry |
Yates NDJ, Brabham RL, Spears RJ, et al. (2019) Chemical Bioconjugation of Proteins in an Undergraduate Lab: One-Pot Oxidation and Derivatization of the N-Terminus Journal of Chemical Education. 96: 1245-1249 |
Budhadev D, Saxby K, Walton J, et al. (2018) Using automated glycan assembly (AGA) for the practical synthesis of heparan sulfate oligosaccharide precursors. Organic & Biomolecular Chemistry |
Spears RJ, Brabham RL, Budhadev D, et al. (2018) Site-selective C-C modification of proteins at neutral pH using organocatalyst-mediated cross aldol ligations. Chemical Science. 9: 5585-5593 |
Brabham RL, Spears RJ, Walton J, et al. (2018) Palladium-unleashed proteins: gentle aldehyde decaging for site-selective protein modification. Chemical Communications (Cambridge, England) |
Mahon CS, McGurk CJ, Watson SMD, et al. (2017) Molecular-recognition mediated transformation of single-chain polymer nanoparticles into crosslinked polymer films. Angewandte Chemie (International Ed. in English) |
Brabham R, Fascione MA. (2017) Pyrrolysine Amber Stop-Codon Suppression: Development and Applications. Chembiochem : a European Journal of Chemical Biology |
Spears RJ, Fascione MA. (2016) Site-selective incorporation and ligation of protein aldehydes. Organic & Biomolecular Chemistry. 14: 7622-38 |