Boris E. Shakhnovich, Ph.D.

Affiliations: 
2014 Boston University, Boston, MA, United States 
Area:
General Biophysics, Genetics, Molecular Biology
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"Boris Shakhnovich"
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Parents

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Charles DeLisi grad student 2014 Boston University
 (A graph-theoretical treatment of protein domain evolution.)
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Publications

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Shakhnovich BE, Shakhnovich EI. (2008) Improvisation in evolution of genes and genomes: whose structure is it anyway? Current Opinion in Structural Biology. 18: 375-81
Zeldovich KB, Chen P, Shakhnovich BE, et al. (2007) A first-principles model of early evolution: emergence of gene families, species, and preferred protein folds. Plos Computational Biology. 3: e139
Lerman G, Shakhnovich BE. (2007) Defining functional distance using manifold embeddings of gene ontology annotations. Proceedings of the National Academy of Sciences of the United States of America. 104: 11334-9
Reddy TE, DeLisi C, Shakhnovich BE. (2007) Binding site graphs: a new graph theoretical framework for prediction of transcription factor binding sites. Plos Computational Biology. 3: e90
Reddy TE, Shakhnovich BE, Roberts DS, et al. (2007) Positional clustering improves computational binding site detection and identifies novel cis-regulatory sites in mammalian GABAA receptor subunit genes. Nucleic Acids Research. 35: e20
Lukatsky DB, Shakhnovich BE, Mintseris J, et al. (2007) Structural similarity enhances interaction propensity of proteins. Journal of Molecular Biology. 365: 1596-606
Shakhnovich BE, Koonin EV. (2006) Origins and impact of constraints in evolution of gene families. Genome Research. 16: 1529-36
Reddy TE, DeLisi C, Shakhnovich BE. (2005) Assessing transcription factor motif drift from noisy decoy sequences. Genome Informatics. International Conference On Genome Informatics. 16: 59-67
Shakhnovich BE. (2005) Improving the precision of the structure-function relationship by considering phylogenetic context. Plos Computational Biology. 1: e9
Shakhnovich BE, Deeds E, Delisi C, et al. (2005) Protein structure and evolutionary history determine sequence space topology. Genome Research. 15: 385-92
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