Mario Ascoli
Affiliations: | 1985-1990 | Population Council Center for Biomedical Research | |
| 1990-2018 | Pharmacology | University of Iowa, Iowa City, IA |
Area:
Receptors and Signal Transduction, Cellular and Molecular EndocrinologyWebsite:
https://medicine.uiowa.edu/pharmacology/profile/mario-ascoliGoogle:
"Mario Ascoli"Bio:
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Parents
Sign in to add mentor| John David Puett | grad student | 1975 | Vanderbilt | |
| (Metabolic Fate of Luteinizing Hormone.) | ||||
Children
Sign in to add trainee| Maria Figueiredo-Pereira | post-doc | 1985-1986 | Population Council Center for Biomedical Research |
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Publications
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| Richards JS, Ascoli M. (2018) Endocrine, Paracrine, and Autocrine Signaling Pathways That Regulate Ovulation. Trends in Endocrinology and Metabolism: Tem |
| Kapfhamer J, Waite C, Ascoli M. (2017) The Gαq/11-provoked induction of Akr1c18 in murine luteal cells is mediated by phospholipase C. Molecular and Cellular Endocrinology |
| Waite C, Mejia R, Ascoli M. (2016) Gq/11-Dependent Changes in the Murine Ovarian Transcriptome at the End of Gestation. Biology of Reproduction |
| Mejia R, Waite C, Ascoli M. (2015) Activation of Gq/11 in the mouse corpus luteum is required for parturition. Molecular Endocrinology (Baltimore, Md.). 29: 238-46 |
| Breen SM, Andric N, Ping T, et al. (2013) Ovulation involves the luteinizing hormone- dependent activation of G |
| Matzkin ME, Yamashita S, Ascoli M. (2013) The ERK1/2 pathway regulates testosterone synthesis by coordinately regulating the expression of steroidogenic genes in Leydig cells. Molecular and Cellular Endocrinology. 370: 130-7 |
| Yamashita S, Tai P, Charron J, et al. (2011) The Leydig cell MEK/ERK pathway is critical for maintaining a functional population of adult Leydig cells and for fertility. Molecular Endocrinology (Baltimore, Md.). 25: 1211-22 |
| Tai P, Ascoli M. (2011) Reactive oxygen species (ROS) play a critical role in the cAMP-induced activation of Ras and the phosphorylation of ERK1/2 in Leydig cells. Molecular Endocrinology (Baltimore, Md.). 25: 885-93 |
| Andric N, Thomas M, Ascoli M. (2010) Transactivation of the epidermal growth factor receptor is involved in the lutropin receptor-mediated down-regulation of ovarian aromatase expression in vivo. Molecular Endocrinology (Baltimore, Md.). 24: 552-60 |
| Tai P, Shiraishi K, Ascoli M. (2009) Activation of the lutropin/choriogonadotropin receptor inhibits apoptosis of immature Leydig cells in primary culture Endocrinology. 150: 3766-3773 |