Masa Negishi
Affiliations: | Receptors | NIEHS/NIH, Durham, NC, United States |
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Collaborators
Sign in to add collaborator| Lalith Perera | collaborator | NIEHS/NIH | |
| Lee G. Pedersen | collaborator | 1995-2015 | NIEHS/NIH |
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Publications
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| Negishi M, Kobayashi K, Sakuma T, et al. (2020) Nuclear receptor phosphorylation in xenobiotic signal transduction. The Journal of Biological Chemistry |
| Fashe M, Hashiguchi T, Negishi M, et al. (2020) Ser100-Phosphorylated ROR Orchestrates CAR and HNF4 to Form Active Chromatin Complex in Response to Phenobarbital to Regulate Induction of CYP2B6. Molecular Pharmacology. 97: 191-201 |
| Shizu R, Yokobori K, Perera L, et al. (2019) Ligand induced dissociation of the AR homodimer precedes AR monomer translocation to the nucleus. Scientific Reports. 9: 16734 |
| Shizu R, Min J, Sobhany M, et al. (2017) Interaction of the phosphorylated DNA-binding domain in nuclear receptor CAR with its ligand binding domain regulates CAR activation. The Journal of Biological Chemistry |
| Shizu R, Osabe M, Perera L, et al. (2017) Phosphorylated nuclear receptor CAR forms a homodimer to repress its constitutive activity for ligand activation. Molecular and Cellular Biology |
| Mutoh S, Sobhany M, Moore R, et al. (2013) Phenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signaling. Science Signaling. 6: ra31 |
| Sobhany M, Kakuta Y, Sugiura N, et al. (2012) The structural basis for a coordinated reaction catalyzed by a bifunctional glycosyltransferase in chondroitin biosynthesis. The Journal of Biological Chemistry. 287: 36022-8 |
| Shindo S, Sakuma T, Negishi M, et al. (2012) Phosphorylation of serine 212 confers novel activity to human estrogen receptor α. Steroids. 77: 448-53 |
| Mutoh S, Osabe M, Inoue K, et al. (2009) Dephosphorylation of threonine 38 is required for nuclear translocation and activation of human xenobiotic receptor CAR (NR1I3). The Journal of Biological Chemistry. 284: 34785-92 |
| Hosseinpour F, Moore R, Negishi M, et al. (2006) Serine 202 regulates the nuclear translocation of constitutive active/androstane receptor. Molecular Pharmacology. 69: 1095-102 |