Heather L Osswald
Affiliations: | The Scripps Research Institute, California, USA |
Area:
Organic Chemistry, medicinal chemistry, chemical biologyGoogle:
"Heather Osswald"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Bhaskar Datta | research assistant | 2009-2011 | Missouri State University |
| Gary A. Meints | research assistant | 2011-2012 | Missouri State University |
| Arun K. Ghosh | grad student | 2012-2017 | Purdue |
| Stuart L. Schreiber | post-doc | 2017- |
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Publications
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| Hudson L, Mason JW, Westphal MV, et al. (2023) Author Correction: Diversity-oriented synthesis encoded by deoxyoligonucleotides. Nature Communications. 14: 7589 |
| Hudson L, Mason JW, Westphal MV, et al. (2023) Diversity-oriented synthesis encoded by deoxyoligonucleotides. Nature Communications. 14: 4930 |
| Ghosh AK, Kovela S, Osswald HL, et al. (2020) Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies. Journal of Medicinal Chemistry |
| Shang M, Feu KS, Vantourout JC, et al. (2019) Modular, stereocontrolled C-H/C-C activation of alkyl carboxylic acids. Proceedings of the National Academy of Sciences of the United States of America |
| Ghosh AK, Jadhav RD, Simpson H, et al. (2018) Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors incorporating aminothiochromane and aminotetrahydronaphthalene carboxamide derivatives as the P2 ligands. European Journal of Medicinal Chemistry. 160: 171-182 |
| Ghosh AK, R Nyalapatla P, Kovela S, et al. (2018) Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure-Activity Studies, Biological and X-ray Structural Analysis. Journal of Medicinal Chemistry |
| Ghosh AK, Rao KV, Nyalapatla PR, et al. (2018) Design of Highly Potent, Dual Acting and Central Nervous System Penetrating HIV-1 Protease Inhibitors with Excellent Potency against Multidrug-Resistant HIV-1 Variants. Chemmedchem |
| Ghosh AK, Rao KV, Nyalapatla PR, et al. (2018) Front Cover: Design of Highly Potent, Dual-Acting and Central-Nervous-System-Penetrating HIV-1 Protease Inhibitors with Excellent Potency against Multidrug-Resistant HIV-1 Variants (ChemMedChem 8/2018) Chemmedchem. 13: 762-762 |
| Aoki M, Hayashi H, Rao KV, et al. (2017) A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency. Elife. 6 |
| Ghosh AK, Rao KV, Nyalapatla PR, et al. (2017) Design and Development of Highly Potent HIV-1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants. Journal of Medicinal Chemistry |