Kui Cheng
Affiliations: | 2009-2014 | Southern Medical University, Guangzhou Shi, Guangdong Sheng, China |
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| Ni C, Zhou L, Yang S, et al. (2024) Oxymatrine, a novel TLR2 agonist, promotes megakaryopoiesis and thrombopoiesis through the STING/NF-κB pathway. Journal of Pharmaceutical Analysis. 15: 101054 |
| Ou J, Zheng L, Chen Y, et al. (2024) Heterocyclic-Modified Imidazoquinoline Derivatives: Selective TLR7 Agonist Regulates Tumor Microenvironment against Melanoma. Journal of Medicinal Chemistry |
| Yang J, Pan Y, Zeng X, et al. (2023) Discovery of novel aporphine alkaloid derivative as potent TLR2 antagonist reversing macrophage polarization and neutrophil infiltration against acute inflammation. Acta Pharmaceutica Sinica. B. 13: 3782-3801 |
| Cen X, Wang B, Liang Y, et al. (2022) Small molecule SMU-CX24 targeting toll-like receptor 3 counteracts inflammation: A novel approach to atherosclerosis therapy. Acta Pharmaceutica Sinica. B. 12: 3667-3681 |
| Chen Z, Zhang L, Yang J, et al. (2021) Design, Synthesis, and Structure-Activity Relationship of -Aryl-'-(thiophen-2-yl)thiourea Derivatives as Novel and Specific Human TLR1/2 Agonists for Potential Cancer Immunotherapy. Journal of Medicinal Chemistry |
| Bi J, Wang W, Du J, et al. (2019) Structure-activity relationship study and biological evaluation of SAC-Garlic acid conjugates as novel anti-inflammatory agents. European Journal of Medicinal Chemistry. 179: 233-245 |
| Cen X, Zhu G, Yang J, et al. (2019) TLR1/2 Specific Small-Molecule Agonist Suppresses Leukemia Cancer Cell Growth by Stimulating Cytotoxic T Lymphocytes. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1802042 |
| Chen Z, Cen X, Yang J, et al. (2019) Synthesis of urea analogues bearing N-alkyl-N'-(thiophen-2-yl) scaffold and evaluation of their innate immune response to toll-like receptors. European Journal of Medicinal Chemistry. 169: 42-52 |
| Chen Z, Cen X, Yang J, et al. (2018) Structure-based discovery of a specific TLR1-TLR2 small molecule agonist from the ZINC drug library database. Chemical Communications (Cambridge, England) |
| Cen X, Liu S, Cheng K. (2018) The Role of Toll-Like Receptor in Inflammation and Tumor Immunity. Frontiers in Pharmacology. 9: 878 |