Brian Henry
Affiliations: | 2005-2007 | Virginia Commonwealth University, Richmond, VA, United States |
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Parents
Sign in to add mentor| Umesh R. Desai | grad student | 2005-2007 | VCU | |
| (PhD: Novel Sulfated 4-HydroxyCinnamic Acid Oligomers as Potent Anticoagulants) | ||||
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Publications
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| Ng S, Brueckner AC, Bahmanjah S, et al. (2022) Discovery and Structure-Based Design of Macrocyclic Peptides Targeting STUB1. Journal of Medicinal Chemistry |
| Henry BL, Desai UR. (2014) Sulfated low molecular weight lignins, allosteric inhibitors of coagulation proteinases via the heparin binding site, significantly alter the active site of thrombin and factor xa compared to heparin. Thrombosis Research. 134: 1123-9 |
| Henry BL, Desai UR. (2014) Discovery methodology for the development of direct factor VIIa inhibitors. Expert Opinion On Drug Discovery. 9: 859-72 |
| Henry BL, Thakkar JN, Liang A, et al. (2012) Sulfated, low molecular weight lignins inhibit a select group of heparin-binding serine proteases. Biochemical and Biophysical Research Communications. 417: 382-6 |
| Henry BL. (2012) CHARACTERIZING THE MOLECULAR CHANGES OF THE THROMBIN ACTIVE SITE INDUCED BY THE ALLOSTERIC BINDING OF SULFATED LOW MOLECULAR WEIGHT LIGNINS, A NOVEL CLASS EXOSITE II DIRECT THROMBIN INHIBITORS Journal of the American College of Cardiology. 59: E2060 |
| Henry BL, Abdel Aziz M, Zhou Q, et al. (2010) Sulfated, low-molecular-weight lignins are potent inhibitorsof plasmin, in addition to thrombin and factor Xa: Novel opportunity for controlling complex pathologies. Thrombosis and Haemostasis. 103: 507-15 |
| Henry BL, Thakkar JN, Martin EJ, et al. (2009) Characterization of the plasma and blood anticoagulant potential of structurally and mechanistically novel oligomers of 4-hydroxycinnamic acids. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 20: 27-34 |
| Henry BL, Connell J, Liang A, et al. (2009) Interaction of antithrombin with sulfated, low molecular weight lignins: opportunities for potent, selective modulation of antithrombin function. The Journal of Biological Chemistry. 284: 20897-908 |
| Henry BL, Desai UR. (2008) Recent research developments in the direct inhibition of coagulation proteinases--inhibitors of the initiation phase. Cardiovascular & Hematological Agents in Medicinal Chemistry. 6: 323-36 |
| Henry BL, Monien BH, Bock PE, et al. (2007) A novel allosteric pathway of thrombin inhibition: Exosite II mediated potent inhibition of thrombin by chemo-enzymatic, sulfated dehydropolymers of 4-hydroxycinnamic acids. The Journal of Biological Chemistry. 282: 31891-9 |