Georgios I Karras, PhD

Affiliations: 
The University of Texas MD Anderson Cancer Center 
Area:
Protein folding, genome maintenance, cancer, evolution, aging
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"Georgios Karras"
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Publications

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Gracia B, Montes P, Gutierrez AM, et al. (2023) Protein-Folding Chaperones Predict Structure-Function Relationships and Cancer Risk in Mutation Carriers. Biorxiv : the Preprint Server For Biology
Economos NG, Thapar U, Balasubramanian N, et al. (2022) An ELISA-based platform for rapid identification of structure-dependent nucleic acid-protein interactions detects novel DNA triplex interactors. The Journal of Biological Chemistry. 102398
Pedley AM, Karras GI, Zhang X, et al. (2018) The Role of HSP90 in the Regulation of de novo Purine Biosynthesis. Biochemistry
Karras GI, Yi S, Sahni N, et al. (2017) HSP90 Shapes the Consequences of Human Genetic Variation. Cell
Sahni N, Yi S, Taipale M, et al. (2015) Widespread macromolecular interaction perturbations in human genetic disorders. Cell. 161: 647-60
Nicolae CM, Aho ER, Vlahos AH, et al. (2014) The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance. The Journal of Biological Chemistry. 289: 13627-37
Karras GI, Fumasoni M, Sienski G, et al. (2013) Noncanonical role of the 9-1-1 clamp in the error-free DNA damage tolerance pathway. Molecular Cell. 49: 536-46
Taipale M, Krykbaeva I, Koeva M, et al. (2012) Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Cell. 150: 987-1001
Karras GI, Jentsch S. (2010) The RAD6 DNA damage tolerance pathway operates uncoupled from the replication fork and is functional beyond S phase. Cell. 141: 255-67
Moertl S, Karras GI, Wismüller T, et al. (2008) Regulation of double-stranded DNA gap repair by the RAD6 pathway. Dna Repair. 7: 1893-906
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