David Robinson Goodlett, MS, PhD
Affiliations: | 2000-2004 | Proteomics | Institute for Systems Biology, Seattle, Seattle, WA, United States |
| 2004-2012 | Medicinal Chemistry | University of Washington School of Pharmacy | |
| 2013-2019 | Pharmaceutical Sciences | University of Maryland School of Pharmacy | |
| 2019-2020 | Microbial Pathogenesis | University of Maryland School of Dentistry | |
| 2020- | Biochemistry and Microbiology | University of Victoria, Victoria, British Columbia, Canada |
Area:
structure function relationships in proteins and lipids iWebsite:
http://goodlettlab.org/Google:
"David R Goodlett"Bio:
Prof Goodlett has spent his career using mass spectrometry to solve structure-function relationships via novel technology and software developments. This work has been in a variety of fields including medicine, oceanography, pharmacy and microbiology all which have led to > 250 publications producing an h-index ~ 70 as of 2019. You can find him online at https://twitter.com/goodlettlab1.
He holds a BS (1982) and MS (1986) degree in chemistry from Auburn University and obtained a PhD in biochemistry from NC State University (1991) with Richard B van Breemen who trained with Catherine Fenselau. His postdoctoral training (1991-1993) was with Richard D Smith on Native MS and ESI fundamentals after which he spent five years in the pharmaceutical industry before returning to academics. Once there he was mentored by Profs Aebersold and Hood.
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Parents
Sign in to add mentor| Frank F. Bartol | research assistant | 1982-1986 | Animal Science (Cell Biology Tree) | |
| (I worked for Skip as a technician and he served as an advisor during my MS degree) | ||||
| John L. Aull | grad student | 1982-1986 | chemistry | |
| (John was my primary mentor during my MS degree) | ||||
| Frank Bradley Armstrong | grad student | 1991 | NCSU | |
| (Characterization of formylated peptides and Manduca Sexta juvenile hormone esterase.) | ||||
| Richard B. Van Breemen | grad student | 1986-1991 | NCSU | |
| (Richard served as my co-advisor along with F B Armstrong) | ||||
| Richard Dale Smith | post-doc | 1991-1993 | PNNL | |
| Ruedi Aebersold | research scientist | 1997-1999 | University of Washington | |
| (I worked with Ruedi both at Univ WA and ISB when he joined in 2001-2004 when I departed) | ||||
| Leroy Hood | research scientist | 2000-2003 | ||
| (Lee hired me to setup proteomics in early 2000) | ||||
Children
Sign in to add traineeCollaborators
Sign in to add collaborator| Robert K Ernst | collaborator | 2000- | University of Maryland Dental School | |
| (co-founded Pataigin with Erik Nilsson formerly of InSilicos) | ||||
| Erik Nilsson | collaborator | 2004- | Deurion and Pataigin | |
| (Erik has been CEO of Deurion and Pataigin. Prior to that founded InSilicos. Began working with him in 2004) | ||||
| Theodore Hupp | collaborator | 2010- | Edinburgh | |
| (Worked with Ted during RASOR years as SAB chair and later at ICCVS in Gdansk. Ted did his PhD at Michigan state Univ. Married to Prof K Ball) | ||||
Publications
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| Mikhael A, Hardie D, Smith D, et al. (2023) Structural Elucidation of Intact Rough-type Lipopolysaccharides Using Field Asymmetric Ion Mobility Spectrometry and Kendrick Mass Defect Plots. Analytical Chemistry |
| Haq S, Oyler BL, Williams E, et al. (2023) Investigating A Multi-Domain Polyketide Synthase in . Marine Drugs. 21 |
| Mikhael A, Hardie D, Smith D, et al. (2023) Structural Elucidation of Intact Rough-Type Lipopolysaccharides using Field Asymmetric Ion Mobility Spectrometry and Kendrick Mass Defect Plots. Biorxiv : the Preprint Server For Biology |
| Pětrošová H, Mikhael A, Culos S, et al. (2023) Lipid A structural diversity among members of the genus . Frontiers in Microbiology. 14: 1181034 |
| Yang H, Sherman ME, Koo CJ, et al. (2023) Structure Determination of Lipid A with Multiple Glycosylation Sites by Tandem MS of Lithium-Adducted Negative Ions. Journal of the American Society For Mass Spectrometry |
| Välikangas T, Suomi T, Chandler CE, et al. (2022) Benchmarking tools for detecting longitudinal differential expression in proteomics data allows establishing a robust reproducibility optimization regression approach. Nature Communications. 13: 7877 |
| Sherman ME, Smith RD, Gardner FM, et al. (2022) A Sensitive GC-MS Method for Quantitation of Lipid A Backbone Components and Terminal Phosphate Modifications. Journal of the American Society For Mass Spectrometry |
| Yang H, Smith RD, Sumner KP, et al. (2022) A Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Direct-from-Urine-Specimen Diagnostic for Gram-Negative Pathogens. Microbiology Spectrum. e0373022 |
| Zik JJ, Yoon SH, Guan Z, et al. (2022) Caulobacter lipid A is conditionally dispensable in the absence of fur and in the presence of anionic sphingolipids. Cell Reports. 39: 110888 |
| Yang H, Smith RD, Chandler CE, et al. (2022) Lipid A Structural Determination from a Single Colony. Analytical Chemistry |