Sean M. Kerwin, Ph.D.

Affiliations: 
University of Texas at Austin, Austin, Texas, U.S.A. 
 Texas State University, San Marcos, TX, United States 
Area:
Synthetic Medicinal Chemistry, Nucleic Acids Chemistry, Natural Products Chemistry, Computational Chemistry
Website:
http://kerwinlab.com
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"Sean Kerwin"
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SNBCP

Parents

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Clayton H. Heathcock grad student 1984-1989 UC Berkeley
George L. Kenyon post-doc 1989-1991 UCSF

Children

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Jeannie Li grad student UT Autin
Wendi M. David grad student 2000 UT Austin
Jonathan T. Kern grad student 2002 UT Austin
Liping Feng grad student 2005 UT Austin
Asha K. Nadipuram grad student 2005 UT Austin
Mireya L. McKee grad student 2007 UT Austin
Bodin Tuesuwan grad student 2007 UT Austin
Dominic McBrayer grad student 2015 UT Austin
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Publications

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McBrayer D, Schoonover M, Long KJ, et al. (2019) N-Methylmesoporphyrin IX Exhibits G-quadruplex Specific Photocleavage Activity. Chembiochem : a European Journal of Chemical Biology
Reinus B, Kerwin SM. (2019) Preparation and Utility of -Alkynyl Azoles in Synthesis. Molecules (Basel, Switzerland). 24
Reinus BJ, Kerwin SM. (2019) N-Alkynyl Pyrrole Based Total Synthesis of Shensongine A Synthesis. 51: 4085-4105
Del Mundo IM, Zewail-Foote M, Kerwin SM, et al. (2017) Alternative DNA structure formation in the mutagenic human c-MYC promoter. Nucleic Acids Research
Reinus B, Kerwin S. (2017) A Copper-Catalyzed N-Alkynylation Route to 2-Substituted N-Alkynyl Pyrroles and Their Cyclization into Pyrrolo[2,1-c]oxazin-1-ones: A Formal Total Synthesis of Peramine Synthesis. 49: 2544-2554
McBrayer D, Kerwin SM. (2015) Synthesis and Evaluation of a Rationally Designed Click-Based Library for G-Quadruplex Selective DNA Photocleavage. Molecules (Basel, Switzerland). 20: 16446-65
Kerwin SM, David WM. (2015) G-quadruplex dynamics: Assays for intramolecular G-quadruplex helicases and inhibitors Biological Relevance and Therapeutic Applications of Dna and Rna Quadruplexes. 85-99
Kerwin SM, Cha J. (2014) A concise synthesis of rooperol and related 1,5-diarylpent-1-en-4-ynes Tetrahedron Letters. 55: 137-141
Schoonover M, Kerwin SM. (2012) G-quadruplex DNA cleavage preference and identification of a perylene diimide G-quadruplex photocleavage agent using a rapid fluorescent assay Bioorganic and Medicinal Chemistry. 20: 6904-6918
Schoonover M, Kerwin SM. (2012) G-quadruplex DNA cleavage preference and identification of a perylene diimide G-quadruplex photocleavage agent using a rapid fluorescent assay Bioorganic and Medicinal Chemistry. 20: 6904-6918
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