Brian C Smith

Affiliations: 
Medical College of Wisconsin 
Area:
acetylation, bromodomains, sirtuins
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"Brian Smith"
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Publications

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Yang M, Smith BC. (2023) Cysteine and methionine oxidation in thrombotic disorders. Current Opinion in Chemical Biology. 76: 102350
Yang M, Chiu J, Scartelli C, et al. (2023) Sulfenylation links oxidative stress to protein disulfide isomerase oxidase activity and thrombus formation. Journal of Thrombosis and Haemostasis : Jth
AbuEid M, Keyes RF, McAllister D, et al. (2022) Fluorinated triphenylphosphonium analogs improve cell selectivity and detection of mito-metformin. Iscience. 25: 105670
Fisher CL, Fallot LB, Wan TC, et al. (2022) Characterization of Dual-Acting A Adenosine Receptor Positive Allosteric Modulators That Preferentially Enhance Adenosine-Induced Gα and Gα Isoprotein Activation. Acs Pharmacology & Translational Science. 5: 625-641
Sprague DJ, Getschman AE, Fenske TG, et al. (2021) Trisubstituted 1,3,5-Triazines: The First Ligands of the sY12-Binding Pocket on Chemokine CXCL12. Acs Medicinal Chemistry Letters. 12: 1773-1782
Yang M, Li W, Harberg C, et al. (2020) Cysteine sulfenylation by CD36 signaling promotes arterial thrombosis in dyslipidemia. Blood Advances. 4: 4494-4507
Goetz CJ, Sprague DJ, Smith BC. (2020) Development of activity-based probes for the protein deacylase Sirt1. Bioorganic Chemistry. 104: 104232
Kalous KS, Wynia-Smith SL, Summers SB, et al. (2020) Human sirtuins are differentially sensitive to inhibition by nitrosating agents and other cysteine oxidants. The Journal of Biological Chemistry
Olp MD, Sprague DJ, Goetz CJ, et al. (2020) Covalent-fragment screening of BRD4 identifies a ligandable site orthogonal to the acetyl-lysine binding sites. Acs Chemical Biology
Lipinski RAJ, Wynia-Smith S, Nord J, et al. (2020) 2131-P: BET Bromodomain Inhibition Upregulates SIRT1 In Pancreatic ß-Cells Diabetes. 69
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