Keyong O-K Chang
Affiliations: | Veterinary Medicine | Kansas State University, Manhattan, KS, United States |
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Rathnayake AD, Zheng J, Kim Y, et al. (2020) 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Science Translational Medicine |
Chang KO, Kim Y, Lovell S, et al. (2019) Antiviral Drug Discovery: Norovirus Proteases and Development of Inhibitors. Viruses. 11 |
Perera KD, Galasiti Kankanamalage AC, Rathnayake AD, et al. (2018) Protease inhibitors broadly effective against feline, ferret and mink coronaviruses. Antiviral Research |
Dang W, Xu L, Ma B, et al. (2018) Nitazoxanide Inhibits Human Norovirus Replication and Synergizes with Ribavirin by Activation of Cellular Antiviral Response. Antimicrobial Agents and Chemotherapy |
Galasiti Kankanamalage AC, Kim Y, Damalanka VC, et al. (2018) Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element. European Journal of Medicinal Chemistry. 150: 334-346 |
Kim Y, Chang KO. (2018) Protein Disulfide Isomerases as potential therapeutic targets for Influenza A and B Viruses. Virus Research |
Damalanka VC, Kim Y, Galasiti Kankanamalage AC, et al. (2018) Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease. European Journal of Medicinal Chemistry. 143: 881-890 |
Pedersen NC, Kim Y, Liu H, et al. (2017) Efficacy of a 3C-like protease inhibitor in treating various forms of acquired feline infectious peritonitis. Journal of Feline Medicine and Surgery. 1098612X17729626 |
Dang W, Yin Y, Wang Y, et al. (2017) Inhibition of calcineurin or IMPDH exerts moderate to potent antiviral activity against norovirus replication. Antimicrobial Agents and Chemotherapy |
Galasiti Kankanamalage AC, Kim Y, Rathnayake AD, et al. (2017) Design, Synthesis, and Evaluation of Novel Prodrugs of Transition State Inhibitors of Norovirus 3CL Protease. Journal of Medicinal Chemistry |