Barry O'Keefe
Affiliations: | 1994-1996 | Laboratory of Drug Discovery Research & Development | National Cancer Institute, Rockville, MD, United States |
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Senadeera SPD, Wang D, Wilson BAP, et al. (2024) Acroamine A, a 2-Amino Adenine Alkaloid from the Marine Soft Coral and Its Semisynthetic Derivatives That Inhibit cAMP-Dependent Protein Kinase A Catalytic Subunit Alpha. Journal of Natural Products |
Khong QT, Smith EA, Wendt KL, et al. (2024) Chemoreactive 2,5-Diketopiperazines from a sp., Structure Revision of Reported Analogues and Proposed Facile Transformation Pathways. Journal of Natural Products |
Kim YY, Gryder BE, Sinniah R, et al. (2024) KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nature Communications. 15: 1703 |
Wang D, Jiang W, Churiwal M, et al. (2024) Neopetrotaurines A-C, Isoquinoline Alkaloids with an Unprecedented Taurine Bridge from the Sponge sp. Journal of Natural Products |
Orfanoudaki M, Akee RK, Martínez-Fructuoso L, et al. (2024) Formation of Trideuteromethylated Artifacts of Pyrrole-Containing Natural Products. Journal of Natural Products |
Du L, Wilson BAP, Li N, et al. (2023) Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases. Journal of Natural Products |
Tian X, Wang D, Jiang W, et al. (2023) Rare Caulamidine Hexacyclic Alkaloids from the Marine Ascidian sp. Journal of Natural Products |
Wilson BAP, Li N, Martinez Fiesco JA, et al. (2023) Biochemical Discovery, Intracellular Evaluation, and Crystallographic Characterization of Synthetic and Natural Product Adenosine 3',5'-Cyclic Monophosphate-Dependent Protein Kinase A (PKA) Inhibitors. Acs Pharmacology & Translational Science. 6: 633-650 |
Jiang W, Tian X, Wang D, et al. (2022) Dentithecamides A-H, Diacylated Zoanthoxanthin Derivatives with PAX3-FOXO1 Inhibitory Activity from the Hydroid . Journal of Natural Products |
Jiang W, Wang D, Wilson BAP, et al. (2021) Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge . Marine Drugs. 19 |