Susan Biggins
Affiliations: | Biochemistry | Fred Hutchinson Cancer Research Center, Seattle, WA, United States |
Area:
Regulation of chromosome segregationWebsite:
http://sharedresources.fhcrc.org/profile/biggins-sueGoogle:
"Susan Biggins"Bio:
http://labs.fhcrc.org/biggins/index.html
Mean distance: 10.65 | S | N | B | C | P |
Parents
Sign in to add mentorMark D. Rose | grad student | 1995 | Princeton | |
(Analysis of Genes that Interact with CDC31, the Yeast Homologue of Centrin) |
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Publications
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Koch LB, Opoku KN, Deng Y, et al. (2019) Autophosphorylation is sufficient to release Mps1 kinase from native kinetochores. Proceedings of the National Academy of Sciences of the United States of America |
Leontiou I, London N, May KM, et al. (2019) The Bub1-TPR Domain Interacts Directly with Mad3 to Generate Robust Spindle Checkpoint Arrest. Current Biology : Cb |
Lang J, Barber A, Biggins S. (2018) An assay for de novo kinetochore assembly reveals a key role for the CENP-T pathway in budding yeast. Elife. 7 |
Gupta A, Evans RK, Koch LB, et al. (2018) Purification of kinetochores from the budding yeast Saccharomyces cerevisiae. Methods in Cell Biology. 144: 349-370 |
Tubman ES, Biggins S, Odde DJ. (2017) Stochastic Modeling Yields a Mechanistic Framework for Spindle Attachment Error Correction in Budding Yeast Mitosis. Cell Systems |
Opoku KN, Koch L, Biggins S, et al. (2017) What Silences the Spindle Checkpoint? A Single Particle Study Biophysical Journal. 112: 431a |
Miller MP, Asbury CL, Biggins S. (2016) A TOG Protein Confers Tension Sensitivity to Kinetochore-Microtubule Attachments. Cell. 165: 1428-39 |
Biggins S. (2015) Under Tension: Kinetochores and Basic Research. Genetics. 200: 681-2 |
Umbreit NT, Miller MP, Tien JF, et al. (2014) Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation. Nature Communications. 5: 4951 |
Sarangapani KK, Duro E, Deng Y, et al. (2014) Sister kinetochores are mechanically fused during meiosis I in yeast. Science (New York, N.Y.). 346: 248-51 |