Brandon J Turunen

Affiliations: 
GSK, Rixensart, Wallonie, Belgium 
Area:
Medicinal Chemistry, Chemical biology and ImmunoOncology
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"Brandon Turunen"
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Publications

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Niphakis MJ, Turunen BJ, Georg GI. (2010) Synthesis of 6- and 7-membered cyclic enaminones: scope and mechanism. The Journal of Organic Chemistry. 75: 6793-805
Ward TR, Turunen BJ, Haack T, et al. (2009) Synthesis of a quinolone library from ynones. Tetrahedron Letters. 50: 6494-9497
Turunen BJ, Ge H, Oyetunji J, et al. (2008) Paclitaxel succinate analogs: Anionic and amide introduction as a strategy to impart blood-brain barrier permeability. Bioorganic & Medicinal Chemistry Letters. 18: 5971-4
Kimball FS, Turunen BJ, Ellis KC, et al. (2008) Enantiospecific synthesis and cytotoxicity of 7-(4-methoxyphenyl)-6-phenyl-2,3,8,8a-tetrahydroindolizin-5(1H)-one enantiomers. Bioorganic & Medicinal Chemistry. 16: 4367-77
Wang X, Turunen BJ, Leighty MW, et al. (2007) Microwave-assisted Suzuki-Miyaura couplings on α-iodoenaminones. Tetrahedron Letters. 48: 8811-8814
Turunen BJ, Georg GI. (2006) Amino acid-derived enaminones: a study in ring formation providing valuable asymmetric synthons. Journal of the American Chemical Society. 128: 8702-3
Spletstoser JT, Turunen BJ, Desino K, et al. (2006) Single-site chemical modification at C10 of the baccatin III core of paclitaxel and Taxol C reduces P-glycoprotein interactions in bovine brain microvessel endothelial cells. Bioorganic & Medicinal Chemistry Letters. 16: 495-8
Georg G, Turunen B. (2006) Synthesis of Cyclic and Bicyclic Enaminones from β-Amino Acids Synfacts. 2006: 1000-1000
White JM, Tunoori AR, Turunen BJ, et al. (2004) [Bis(2-methoxyethyl)amino]sulfur trifluoride, the Deoxo-Fluor reagent: application toward one-flask transformations of carboxylic acids to amides. The Journal of Organic Chemistry. 69: 2573-6
Rice A, Michaelis ML, Georg G, et al. (2003) Overcoming the blood-brain barrier to taxane delivery for neurodegenerative diseases and brain tumors. Journal of Molecular Neuroscience : Mn. 20: 339-43
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