Nicholas A Meanwell
Affiliations: | Bristol-Myers Squibb Research and Development |
Area:
Medicinal ChemistryGoogle:
"Nicholas Meanwell"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| D. Neville Jones | grad student | 1976-1979 | University of Sheffield |
| Carl Randolph Johnson | post-doc | 1979-1982 | Wayne State |
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Publications
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| Liu J, Han J, Izawa K, et al. (2020) Cyclic tailor-made amino acids in the design of modern pharmaceuticals. European Journal of Medicinal Chemistry. 208: 112736 |
| Sivaprakasam P, Wang Z, Meanwell NA, et al. (2020) Structure-based amelioration of PXR transactivation in a novel series of macrocyclic allosteric inhibitors of HIV-1 integrase. Bioorganic & Medicinal Chemistry Letters. 127531 |
| Patel M, Cianci C, Allard CW, et al. (2020) Design, Synthesis and SAR Study of Novel C2-Pyrazolopyrimidine Amides and Amide Isosteres as Allosteric Integrase Inhibitors. Bioorganic & Medicinal Chemistry Letters. 127516 |
| Patel M, Naidu BN, Dicker I, et al. (2020) Design, synthesis and SAR study of bridged tricyclic pyrimidinone carboxamides as HIV-1 integrase inhibitors. Bioorganic & Medicinal Chemistry. 115541 |
| Mei H, Han J, White S, et al. (2020) Tailor-Made Amino Acids and Fluorinated Motifs as Prominent Traits in the Modern Pharmaceuticals. Chemistry (Weinheim An Der Bergstrasse, Germany) |
| Li G, Meanwell NA, Krystal MR, et al. (2020) Discovery and Optimization of Novel Pyrazolopyrimidines as Potent and Orally Bioavailable Allosteric HIV-1 Integrase Inhibitors. Journal of Medicinal Chemistry |
| Oderinde MS, Mao E, Ramirez A, et al. (2020) Synthesis of Cyclobutane-Fused Tetracyclic Scaffolds via Visible-Light Photocatalysis for Building Molecular Complexity. Journal of the American Chemical Society |
| Karmakar A, Ramalingam S, Basha M, et al. (2020) Facile Access to 1,4-Disubstituted Pyrrolo[1,2-a]pyrazines from α-Aminoacetonitriles Synthesis. 52: 441-449 |
| Smith D, Krishnananthan S, Meanwell NA, et al. (2020) Multigram Synthesis of BMS-929075, an Allosteric, Palm Site Inhibitor of HCV NS5B Replicase, Involving the Synthesis of a Highly Functionalized Benzofuran through a Telescoped Process Organic Process Research & Development. 24: 1157-1163 |
| Peese KM, Narasimhulu Naidu B, Patel M, et al. (2019) Heterocycle amide isosteres: An approach to overcoming resistance for HIV-1 integrase strand transfer inhibitors. Bioorganic & Medicinal Chemistry Letters. 126784 |