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David L. Nelson, Ph.D.

Affiliations: 
2017 Chemistry The University of Nebraska - Lincoln, Lincoln, NE 
Area:
Biochemistry, Mechanistic Enzymology
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David B. Berkowitz grad student 2017 University of Nebraska - Lincoln

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Graham DL, Beio ML, Nelson DL, et al. (2019) Human Serine Racemase: Key Residues/Active Site Motifs and Their Relation to Enzyme Function. Frontiers in Molecular Biosciences. 6: 8
Nelson DL, Applegate GA, Beio ML, et al. (2017) Human Serine Racemase Structure/Activity Relationship Studies Provide Mechanistic Insight and Point to Position-84 as a Hotspot for β-Elimination Function. The Journal of Biological Chemistry
Panigrahi K, Nelson DL, Berkowitz DB. (2012) Unleashing a "true" pSer-mimic in the cell. Chemistry & Biology. 19: 666-7
Applegate GA, Cheloha RW, Nelson DL, et al. (2011) A new dehydrogenase from Clostridium acetobutylicum for asymmetric synthesis: dynamic reductive kinetic resolution entry into the Taxotère side chain. Chemical Communications (Cambridge, England). 47: 2420-2
Berkowitz DB, Karukurichi KR, de la Salud-Bea R, et al. (2008) Use of Fluorinated Functionality in Enzyme Inhibitor Development: Mechanistic and Analytical Advantages. Journal of Fluorine Chemistry. 129: 731-742
Luiz Oliveira Penido M, Resende DM, Vianello MA, et al. (2007) A new series of schistosomicide drugs, the alkylaminoalkanethiosulfuric acids, partially inhibit the activity of Schistosoma mansoni ATP diphosphohydrolase. European Journal of Pharmacology. 570: 10-7
Magalhães HP, Magalhães A, Juliano L, et al. (2006) Mechanism of action and determination of the best substrate for a thrombin-like enzyme from Lachesis muta muta venom by regression analysis of the kinetic parameters determined with peptidyl p-nitroanilide substrates. Toxicon : Official Journal of the International Society On Toxinology. 47: 453-8
Pech LL, Nelson DL. (1994) Purification and characterization of calmodulin (lysine 115) N-methyltransferase from Paramecium tetraurelia Bba - General Subjects. 1199: 183-194
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