Sabine Ottilie
Affiliations: | Salk and Harvard University |
Area:
yeast; cell cycle; apoptosis; kinases; phosphatases; cancer; malariaGoogle:
"Sabine Ottilie"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Raymond L. Erikson | post-doc | Harvard & Radcliffe | |
| Susan Forsburg | post-doc | USC (PombeTree) |
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Publications
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| Vanaerschot M, Murithi JM, Pasaje CFA, et al. (2020) Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity. Cell Chemical Biology |
| LaMonte GM, Rocamora F, Marapana DS, et al. (2020) Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway. Nature Communications. 11: 1780 |
| Abraham M, Gagaring K, Marino ML, et al. (2020) Probing the Open Global Health Chemical Diversity Library for multistage-active starting points for next-generation antimalarials. Acs Infectious Diseases |
| Singh S, El-Sakkary N, Skinner DE, et al. (2020) Synthesis and Bioactivity of Phthalimide Analogs as Potential Drugs to Treat Schistosomiasis, a Neglected Disease of Poverty. Pharmaceuticals (Basel, Switzerland). 13 |
| Murithi JM, Owen ES, Istvan ES, et al. (2019) Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery. Cell Chemical Biology |
| Mandt REK, Lafuente-Monasterio MJ, Sakata-Kato T, et al. (2019) In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model. Science Translational Medicine. 11 |
| Winzeler EA, Ottilie S. (2019) The proteasome as a target: How not tidying up can have toxic consequences for parasitic protozoa. Proceedings of the National Academy of Sciences of the United States of America. 116: 10198-10200 |
| Antonova-Koch Y, Meister S, Abraham M, et al. (2018) Open-source discovery of chemical leads for next-generation chemoprotective antimalarials. Science (New York, N.Y.). 362 |
| Xie SC, Gillett DL, Spillman NJ, et al. (2018) Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome. Journal of Medicinal Chemistry |
| Ottilie S, Goldgof GM, Cheung AL, et al. (2018) Two inhibitors of yeast plasma membrane ATPase 1 (ScPma1p): toward the development of novel antifungal therapies. Journal of Cheminformatics. 10: 6 |