Hayden Peacock, PhD
Affiliations: | University of Oxford, Oxford, United Kingdom |
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Publications
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Alteen MG, Peacock H, Meek RW, et al. (2022) Potent De Novo Macrocyclic Peptides that Inhibit O-GlcNAc Transferase Through an Allosteric Mechanism. Angewandte Chemie (International Ed. in English) |
Dai SA, Hu Q, Gao R, et al. (2022) State-selective modulation of heterotrimeric Gαs signaling with macrocyclic peptides. Cell |
Peacock H, Suga H. (2021) Discovery of De Novo Macrocyclic Peptides by Messenger RNA Display. Trends in Pharmacological Sciences |
Peacock H, Henriques ST, Benfield AH, et al. (2020) Antimicrobial peptide mimetics based on a diphenylacetylene scaffold: synthesis, conformational analysis and activity. Chemmedchem |
Troeira Henriques S, Peacock H, Benfield AH, et al. (2020) Challenging the Chirality Paradigm in Peptide-Lipid Interactions Biophysical Journal. 118: 343a |
Troeira Henriques S, Peacock H, Benfield A, et al. (2019) Is the mirror image a true reflection? Intrinsic membrane chirality modulates peptide binding. Journal of the American Chemical Society |
Craik DJ, Lee MH, Rehm FBH, et al. (2017) Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffolds. Bioorganic & Medicinal Chemistry |
Peacock H, Luo J, Yamashita T, et al. (2016) Non-covalent S···O interactions control conformation in a scaffold that disrupts islet amyloid polypeptide fibrillation. Chemical Science. 7: 6435-6439 |
Peacock H, Thinnes CC, Kawamura A, et al. (2016) Tetracyanoresorcin[4]arene selectively recognises trimethyllysine and inhibits its enzyme-catalysed demethylation Supramolecular Chemistry. 1-7 |
Ibarra-Soza JM, Morris AA, Jayalath P, et al. (2012) 7-Substituted 8-aza-7-deazaadenosines for modification of the siRNA major groove. Organic & Biomolecular Chemistry. 10: 6491-7 |