Hayden Peacock, PhD

Affiliations: 
University of Oxford, Oxford, United Kingdom 
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"Hayden Peacock"
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Publications

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Alteen MG, Peacock H, Meek RW, et al. (2022) Potent De Novo Macrocyclic Peptides that Inhibit O-GlcNAc Transferase Through an Allosteric Mechanism. Angewandte Chemie (International Ed. in English)
Dai SA, Hu Q, Gao R, et al. (2022) State-selective modulation of heterotrimeric Gαs signaling with macrocyclic peptides. Cell
Peacock H, Suga H. (2021) Discovery of De Novo Macrocyclic Peptides by Messenger RNA Display. Trends in Pharmacological Sciences
Peacock H, Henriques ST, Benfield AH, et al. (2020) Antimicrobial peptide mimetics based on a diphenylacetylene scaffold: synthesis, conformational analysis and activity. Chemmedchem
Troeira Henriques S, Peacock H, Benfield AH, et al. (2020) Challenging the Chirality Paradigm in Peptide-Lipid Interactions Biophysical Journal. 118: 343a
Troeira Henriques S, Peacock H, Benfield A, et al. (2019) Is the mirror image a true reflection? Intrinsic membrane chirality modulates peptide binding. Journal of the American Chemical Society
Craik DJ, Lee MH, Rehm FBH, et al. (2017) Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffolds. Bioorganic & Medicinal Chemistry
Peacock H, Luo J, Yamashita T, et al. (2016) Non-covalent S···O interactions control conformation in a scaffold that disrupts islet amyloid polypeptide fibrillation. Chemical Science. 7: 6435-6439
Peacock H, Thinnes CC, Kawamura A, et al. (2016) Tetracyanoresorcin[4]arene selectively recognises trimethyllysine and inhibits its enzyme-catalysed demethylation Supramolecular Chemistry. 1-7
Ibarra-Soza JM, Morris AA, Jayalath P, et al. (2012) 7-Substituted 8-aza-7-deazaadenosines for modification of the siRNA major groove. Organic & Biomolecular Chemistry. 10: 6491-7
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