Christine Ann Collins

Affiliations: 
1988-1997 Northwestern University, Evanston, IL 
 1997-2018 AbbVie 
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"Christine Ann Collins"
Bio:

https://www.worldcat.org/oclc/11655516
http://www.jbc.org/content/257/2/827.short

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William Wood Wells grad student 1983 Michigan State
 (Phosphorylation of lysosomal membrane components.)
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Publications

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Xin Z, Zhao H, Serby MD, et al. (2008) Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 4298-302
Zhao G, Souers AJ, Voorbach M, et al. (2008) Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor. Journal of Medicinal Chemistry. 51: 380-3
Liu G, Lynch JK, Freeman J, et al. (2007) Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors. Journal of Medicinal Chemistry. 50: 3086-100
Xu H, Wilcox D, Nguyen P, et al. (2007) Hepatic knockdown of stearoyl-CoA desaturase 1 via RNA interference in obese mice decreases lipid content and changes fatty acid composition. Frontiers in Bioscience : a Journal and Virtual Library. 12: 3781-94
Iyengar RR, Lynch JK, Mulhern MM, et al. (2007) An evaluation of 3,4-methylenedioxy phenyl replacements in the aminopiperidine chromone class of MCHr1 antagonists. Bioorganic & Medicinal Chemistry Letters. 17: 874-8
Souers AJ, Iyengar RR, Judd AS, et al. (2007) Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: the effects of chirality on substituted indan-1-ylamines. Bioorganic & Medicinal Chemistry Letters. 17: 884-9
Xu H, Wilcox D, Nguyen P, et al. (2006) Hepatic knockdown of mitochondrial GPAT1 in ob/ob mice improves metabolic profile. Biochemical and Biophysical Research Communications. 349: 439-48
Vasudevan A, Souers AJ, Freeman JC, et al. (2005) Aminopiperidine indazoles as orally efficacious melanin concentrating hormone receptor-1 antagonists. Bioorganic & Medicinal Chemistry Letters. 15: 5293-7
Vasudevan A, Wodka D, Verzal MK, et al. (2004) Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 2. Bioorganic & Medicinal Chemistry Letters. 14: 4879-82
Kini AR, Collins CA. (2001) Modulation of cytoplasmic dynein ATPase activity by the accessory subunits. Cell Motility and the Cytoskeleton. 48: 52-60
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