Emily R. Legan

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2017- Emory University, Atlanta, GA 
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"Emily Legan"
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Renhao Li grad student 2017- Emory
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Arce NA, Markham-Lee Z, Liang Q, et al. (2024) Conformational activation and inhibition of von Willebrand factor by targeting its autoinhibitory module. Blood
Legan ER, Liu Y, Arce NA, et al. (2022) Type 2B von Willebrand disease mutations differentially perturb autoinhibition of the A1 domain. Blood
Ito J, Hunter Baldwin W, Cox C, et al. (2021) Removal of single-site N-linked glycans on factor VIII alters binding of domain-specific monoclonal antibodies. Journal of Thrombosis and Haemostasis : Jth
Voos KM, Cao W, Arce NA, et al. (2021) Desialylation of O-glycans activates von Willebrand factor by destabilizing its autoinhibitory module. Journal of Thrombosis and Haemostasis : Jth
Arce NA, Cao W, Brown AK, et al. (2021) Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module. Nature Communications. 12: 2360
Legan ER, Li R. (2019) Gone With the Vane. Arteriosclerosis, Thrombosis, and Vascular Biology. 39: 1702-1704
Legan ER, Li R. (2019) FAM-tastic phospho-regulation of von Willebrand factor activity. Journal of Thrombosis and Haemostasis : Jth
Deng W, Voos KM, Colucci JK, et al. (2018) Delimiting the autoinhibitory module of von Willebrand factor. Journal of Thrombosis and Haemostasis : Jth
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