Emily R. Legan
Affiliations: | 2017- | Emory University, Atlanta, GA |
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Publications
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Arce NA, Markham-Lee Z, Liang Q, et al. (2024) Conformational activation and inhibition of von Willebrand factor by targeting its autoinhibitory module. Blood |
Legan ER, Liu Y, Arce NA, et al. (2022) Type 2B von Willebrand disease mutations differentially perturb autoinhibition of the A1 domain. Blood |
Ito J, Hunter Baldwin W, Cox C, et al. (2021) Removal of single-site N-linked glycans on factor VIII alters binding of domain-specific monoclonal antibodies. Journal of Thrombosis and Haemostasis : Jth |
Voos KM, Cao W, Arce NA, et al. (2021) Desialylation of O-glycans activates von Willebrand factor by destabilizing its autoinhibitory module. Journal of Thrombosis and Haemostasis : Jth |
Arce NA, Cao W, Brown AK, et al. (2021) Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module. Nature Communications. 12: 2360 |
Legan ER, Li R. (2019) Gone With the Vane. Arteriosclerosis, Thrombosis, and Vascular Biology. 39: 1702-1704 |
Legan ER, Li R. (2019) FAM-tastic phospho-regulation of von Willebrand factor activity. Journal of Thrombosis and Haemostasis : Jth |
Deng W, Voos KM, Colucci JK, et al. (2018) Delimiting the autoinhibitory module of von Willebrand factor. Journal of Thrombosis and Haemostasis : Jth |