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Siwei Li

Affiliations: 
2008-2014 Chemistry University of Cincinnati, Cincinnati, OH 
Area:
Metabolomics, Clinical Mass Spectrometry, Drug Metabolism
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"Siwei Li"
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Parents

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Patrick A. Limbach grad student 2014 University of Cincinnati
Duxin Sun post-doc 2017 University of Michigan

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Publications

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Huddle BC, Grimley E, Chtcherbinine M, et al. (2020) Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy. European Journal of Medicinal Chemistry. 211: 113060
Huddle BC, Grimley E, Buchman CD, et al. (2018) Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy. Journal of Medicinal Chemistry
Qin C, Hu Y, Zhou B, et al. (2018) Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression. Journal of Medicinal Chemistry
Zhao Y, Zhou B, Bai L, et al. (2018) Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor. Journal of Medicinal Chemistry
Zhao Y, Bai L, Liu L, et al. (2017) Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor. Journal of Medicinal Chemistry
Yu A, Baker JR, Fioritto AF, et al. (2016) Measurement of in vivo Gastrointestinal Release and Dissolution of Three Locally Acting Mesalamine Formulations in Regions of the Human Gastrointestinal Tract. Molecular Pharmaceutics
Patel TS, Cinti S, Sun D, et al. (2016) Oseltamivir for pandemic influenza preparation: Maximizing the use of an existing stockpile. American Journal of Infection Control
Fioritto AF, Yu A, Baker J, et al. (2016) Mo1318 Direct Comparison of In Vivo Drug Release Profiles of Three Locally-Acting Drug Products of Mesalamine in the Gastrointestinal Tract and Correlation With Systemic Exposure and Fecal Concentrations in Healthy Humans Gastroenterology. 150: S696
Li S, Limbach PA. (2014) Identification of RNA sequence isomer by isotope labeling and LC-MS/MS. Journal of Mass Spectrometry : Jms. 49: 1191-8
Wetzel C, Li S, Limbach PA. (2014) Metabolic de-isotoping for improved LC-MS characterization of modified RNAs. Journal of the American Society For Mass Spectrometry. 25: 1114-23
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