Michael Laskowski, Ph. D.

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1957-2004 Chemistry Purdue University, West Lafayette, IN, United States 
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"Michael Laskowski"
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Publications

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Qasim MA, Wang L, Qasim S, et al. (2013) Additivity-based design of the strongest possible turkey ovomucoid third domain inhibitors for porcine pancreatic elastase (PPE) and Streptomyces griseus protease B (SGPB). Febs Letters. 587: 3021-6
Qasim MA, Song J, Markley JL, et al. (2010) Cleavage of peptide bonds bearing ionizable amino acids at P(1) by serine proteases with hydrophobic S(1) pocket. Biochemical and Biophysical Research Communications. 400: 507-10
Yi Z, Vitek O, Qasim MA, et al. (2006) Functional evolution within a protein superfamily. Proteins. 63: 697-708
Kelly CA, Laskowski M, Qasim MA. (2005) The role of scaffolding in standard mechanism serine proteinase inhibitors Protein and Peptide Letters. 12: 465-471
Li J, Yi Z, Laskowski MC, et al. (2005) Analysis of sequence-reactivity space for protein-protein interactions. Proteins. 58: 661-71
Ganz PJ, Bauer MD, Sun Y, et al. (2004) Stabilized variant of Streptomyces subtilisin inhibitor and its use in stabilizing subtilisin BPN'. Protein Engineering, Design & Selection : Peds. 17: 333-9
LASKOWSKI M, WIDOM JM, MCFADDEN ML, et al. (2003) Differential ultraviolet spectra of insulin. Biochimica Et Biophysica Acta. 19: 581-2
Qasim MA, Lu W, Lu SM, et al. (2003) Testing of the additivity-based protein sequence to reactivity algorithm. Biochemistry. 42: 6460-6
Song J, Laskowski M, Qasim MA, et al. (2003) Two conformational states of Turkey ovomucoid third domain at low pH: three-dimensional structures, internal dynamics, and interconversion kinetics and thermodynamics. Biochemistry. 42: 6380-91
Song J, Laskowski M, Qasim MA, et al. (2003) NMR determination of pKa values for Asp, Glu, His, and Lys mutants at each variable contiguous enzyme-inhibitor contact position of the turkey ovomucoid third domain. Biochemistry. 42: 2847-56
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