Vedagopuram Sreekanth

Affiliations: 
Broad Institute of MIT and Harvard, USA 
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"Vedagopuram Sreekanth"
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Mercer JAM, DeCarlo SJ, Roy Burman SS, et al. (2024) Continuous evolution of compact protein degradation tags regulated by selective molecular glues. Science (New York, N.Y.). 383: eadk4422
Nguyen TM, Sreekanth V, Deb A, et al. (2023) Proteolysis-targeting chimeras with reduced off-targets. Nature Chemistry
Wieder N, Fried JC, Kim C, et al. (2023) FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity. Cell Metabolism
Arp CJ, Reynders M, Sreekanth V, et al. (2023) Photoswitchable Molecular Glues Enable Optical Control of Transcription Factor Degradation. Biorxiv : the Preprint Server For Biology
Sreekanth V, Jan M, Zhao KT, et al. (2023) A molecular glue approach to control the half-life of CRISPR-based technologies. Biorxiv : the Preprint Server For Biology
Wieder N, Fried JC, Kim C, et al. (2023) FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity. Biorxiv : the Preprint Server For Biology
Lim D, Zhou Q, Cox KJ, et al. (2022) A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules. Nature Cell Biology
Modell AE, Lim D, Nguyen TM, et al. (2021) CRISPR-based therapeutics: current challenges and future applications. Trends in Pharmacological Sciences
Sreekanth V, Pal S, Kumar S, et al. (2021) Self-assembled supramolecular nanomicelles from a bile acid-docetaxel conjugate are highly tolerable with improved therapeutic efficacy. Biomaterials Science
Sreekanth V, Zhou Q, Kokkonda P, et al. (2020) Chemogenetic System Demonstrates That Cas9 Longevity Impacts Genome Editing Outcomes. Acs Central Science. 6: 2228-2237
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